Hematologic profile of heterozygous (fIIWT/WE) mice
| . | fIIWT/WT . | fIIWT/WE . | fIIWT/Null . |
|---|---|---|---|
| WBCs, ×109/L | 3.2 ± 0.5 | 3.5 ± 1.2 | 7.4 ± 2.6 |
| RBCs, ×1012/L | 8.1 ± 1.6 | 7.9 ± 2.4 | 7.7 ± 1.5 |
| Hemoglobin, g/dL | 13.9 ± 0.4 | 13.8 ± 0.8 | 11.4 ± 0.3 |
| Hematocrit, % | 42.4 ± 8.4 | 40.4 ± 12.2 | 39.4 ± 7.5 |
| Platelets, ×109/L | 620 ± 129 | 580 ± 128 | 755 ± 114 |
| PT, s | 10.4 ± 0.1 | 11.2 ± 0.1 | 11.3 ± 0.1 |
| aPTT, s | 26.3 ± 0.6 | 24.9 ± 1.9 | 26.5 ± 0.9 |
| Tail bleeding time, s | 119 ± 12 | 164 ± 7* | 119 ± 7 |
| . | fIIWT/WT . | fIIWT/WE . | fIIWT/Null . |
|---|---|---|---|
| WBCs, ×109/L | 3.2 ± 0.5 | 3.5 ± 1.2 | 7.4 ± 2.6 |
| RBCs, ×1012/L | 8.1 ± 1.6 | 7.9 ± 2.4 | 7.7 ± 1.5 |
| Hemoglobin, g/dL | 13.9 ± 0.4 | 13.8 ± 0.8 | 11.4 ± 0.3 |
| Hematocrit, % | 42.4 ± 8.4 | 40.4 ± 12.2 | 39.4 ± 7.5 |
| Platelets, ×109/L | 620 ± 129 | 580 ± 128 | 755 ± 114 |
| PT, s | 10.4 ± 0.1 | 11.2 ± 0.1 | 11.3 ± 0.1 |
| aPTT, s | 26.3 ± 0.6 | 24.9 ± 1.9 | 26.5 ± 0.9 |
| Tail bleeding time, s | 119 ± 12 | 164 ± 7* | 119 ± 7 |
WBC indicates white blood cells.
P < .02, Student t test comparing fIIWT/WT or fIIWT/Null with fIIWT/WE (n = 6 per genotype except for tail bleeding time, which is n = 7).