Obstetric and thrombotic histories and aPL of women before pregnancy treated with additional prednisolone
Patient . | Previous Thrombo-embolism . | Fetal loss at < 10 weeks: treatment . | Fetal loss at > 10 weeks: treatment . | IUGR . | Preeclampsia . | Live births; gestation . | LA . | Ig M ACA < 11MPL U/mL . | Ig G ACA < 20.1GPL U/mL . | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
None . | Aspirin . | Aspirin/heparin . | None . | Aspirin . | Aspirin/heparin . | ||||||||
1 | 0 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | + | 14.6 | 3.7 |
2 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | + | 16.4 | 13.3 |
3 | 0 | 7 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 1; 28/40 | + | 9.8 | 70 |
4 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 1; 38/40 | + | 74 | > 300 |
5 | 1 | 0 | 0 | 1 | 0 | 0 | 2; No aspirin* | 0 | 0 | 0 | + | 6.5 | 30.8 |
6 | 3 | 1 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 1; 37/40 | + | 18 | 105 |
7 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | − | 14.5 | 24.2 |
8 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 1† | + | 26.2 | 7.2 |
9 | 0 | 6 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | + | 7.5 | 11.5 |
10 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | + | 5 | 18.4 |
11 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | ‡ | 11.1 | 93.8 |
12 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | + | 5.7 | 4.7 |
13 | 0 | 5 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | + | 9.4 | 8.1 |
14 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | + | 11.9 | 140 |
15 | 0 | 3 | 2 | 3 | 1 | 0 | 0 | 0 | 0 | 1; 40/40 | − | 13 | 9 |
16 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | − | 32.7 | 79.2 |
17 | 0 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | − | 15.5 | 3.3 |
18 | 0 | 3 | 0 | 1; Allergic to LMWH; limited use§ | 0 | 0 | 0 | 1; Aspirin; allergic to LMWH§ | 0 | 1; 40/40 | + | 1.5 | 1.1 |
Patient . | Previous Thrombo-embolism . | Fetal loss at < 10 weeks: treatment . | Fetal loss at > 10 weeks: treatment . | IUGR . | Preeclampsia . | Live births; gestation . | LA . | Ig M ACA < 11MPL U/mL . | Ig G ACA < 20.1GPL U/mL . | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
None . | Aspirin . | Aspirin/heparin . | None . | Aspirin . | Aspirin/heparin . | ||||||||
1 | 0 | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | + | 14.6 | 3.7 |
2 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | + | 16.4 | 13.3 |
3 | 0 | 7 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 1; 28/40 | + | 9.8 | 70 |
4 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 1; 38/40 | + | 74 | > 300 |
5 | 1 | 0 | 0 | 1 | 0 | 0 | 2; No aspirin* | 0 | 0 | 0 | + | 6.5 | 30.8 |
6 | 3 | 1 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 1; 37/40 | + | 18 | 105 |
7 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | − | 14.5 | 24.2 |
8 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 1† | + | 26.2 | 7.2 |
9 | 0 | 6 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | + | 7.5 | 11.5 |
10 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | + | 5 | 18.4 |
11 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | ‡ | 11.1 | 93.8 |
12 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | + | 5.7 | 4.7 |
13 | 0 | 5 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | + | 9.4 | 8.1 |
14 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | + | 11.9 | 140 |
15 | 0 | 3 | 2 | 3 | 1 | 0 | 0 | 0 | 0 | 1; 40/40 | − | 13 | 9 |
16 | 0 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | − | 32.7 | 79.2 |
17 | 0 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | − | 15.5 | 3.3 |
18 | 0 | 3 | 0 | 1; Allergic to LMWH; limited use§ | 0 | 0 | 0 | 1; Aspirin; allergic to LMWH§ | 0 | 1; 40/40 | + | 1.5 | 1.1 |
IUGR indicates intrauterine growth restriction; LA, lupus anticoagulant; ACA, anticardiolipin antibodies (IgM and IgG); and LMWH, low-molecular-weight heparin.
Intolerant of aspirin; therefore, LMWH alone was given.
Gestational age at delivery unavailable.
Result not available.
Urticaria at injection sites with LMWH; therefore, LMWH was discontinued.