Table 4

CD36 SNPs associated with published phenotypes and showing evidence of association with platelet CD36 expression

SNPRank*PLit PDirection§PhenotypeReference
rs3211870 0.00000127 0.0079 −+ HDL 26  
rs3211870 0.00000127 0.005 ++ TMP 27  
rs3211849 0.00000172 0.029 −+ HDL 26  
rs7807607 0.00000211 0.07 ++ MS 30  
rs3211842 0.00000218 0.00074 +− HDL 26  
rs1358337 0.00000344 0.00066 −+ HDL 26  
rs1761667 0.00000417 0.00035 ++ TMP 27  
rs1761667 0.00000417 0.028 +− FFA 29  
rs1049654 10 0.00000560 0.0028 −+ HDL 26  
rs10499859 15 0.00000921 0.003 − TMP 27  
rs10499859 15 0.00000921 0.00028 −+ HDL 26  
rs3211867 19 0.00000951 0.003 ++ Obesity 31  
rs9784998 20 0.00000951 0.026 ++ TMP 27  
rs9784998 20 0.00000951 0.015 +− HDL 26  
rs3211883 27 0.000298 0.007 ++ Obesity 31  
rs3211908 31 0.00212 0.0005 ++ Obesity 31  
rs1984112 35 0.00788 0.008 +− FFA 29  
rs2151916 43 0.0221 0.02 +− LDL 28  
SNPRank*PLit PDirection§PhenotypeReference
rs3211870 0.00000127 0.0079 −+ HDL 26  
rs3211870 0.00000127 0.005 ++ TMP 27  
rs3211849 0.00000172 0.029 −+ HDL 26  
rs7807607 0.00000211 0.07 ++ MS 30  
rs3211842 0.00000218 0.00074 +− HDL 26  
rs1358337 0.00000344 0.00066 −+ HDL 26  
rs1761667 0.00000417 0.00035 ++ TMP 27  
rs1761667 0.00000417 0.028 +− FFA 29  
rs1049654 10 0.00000560 0.0028 −+ HDL 26  
rs10499859 15 0.00000921 0.003 − TMP 27  
rs10499859 15 0.00000921 0.00028 −+ HDL 26  
rs3211867 19 0.00000951 0.003 ++ Obesity 31  
rs9784998 20 0.00000951 0.026 ++ TMP 27  
rs9784998 20 0.00000951 0.015 +− HDL 26  
rs3211883 27 0.000298 0.007 ++ Obesity 31  
rs3211908 31 0.00212 0.0005 ++ Obesity 31  
rs1984112 35 0.00788 0.008 +− FFA 29  
rs2151916 43 0.0221 0.02 +− LDL 28  

All SNPs from supplemental Table 1 with P < .05 from the white subset analysis ordered by P value.

TMP indicates total monocyte CD36 protein; MS, metabolic syndrome; and FFA, free fatty acids.

*

Rank indicates rank of SNP by P value in supplemental Table 1.

P value from supplemental Table 1.

Reported P value in study for association with phenotype.

§

Direction of SNP effect on CD36 expression, direction of SNP effect reported in study for association with phenotype.

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