CD36 SNPs associated with published phenotypes and showing evidence of association with platelet CD36 expression
SNP . | Rank* . | P† . | Lit P‡ . | Direction§ . | Phenotype . | Reference . |
---|---|---|---|---|---|---|
rs3211870 | 1 | 0.00000127 | 0.0079 | −+ | HDL | 26 |
rs3211870 | 1 | 0.00000127 | 0.005 | ++ | TMP | 27 |
rs3211849 | 3 | 0.00000172 | 0.029 | −+ | HDL | 26 |
rs7807607 | 5 | 0.00000211 | 0.07 | ++ | MS | 30 |
rs3211842 | 6 | 0.00000218 | 0.00074 | +− | HDL | 26 |
rs1358337 | 7 | 0.00000344 | 0.00066 | −+ | HDL | 26 |
rs1761667 | 8 | 0.00000417 | 0.00035 | ++ | TMP | 27 |
rs1761667 | 8 | 0.00000417 | 0.028 | +− | FFA | 29 |
rs1049654 | 10 | 0.00000560 | 0.0028 | −+ | HDL | 26 |
rs10499859 | 15 | 0.00000921 | 0.003 | − | TMP | 27 |
rs10499859 | 15 | 0.00000921 | 0.00028 | −+ | HDL | 26 |
rs3211867 | 19 | 0.00000951 | 0.003 | ++ | Obesity | 31 |
rs9784998 | 20 | 0.00000951 | 0.026 | ++ | TMP | 27 |
rs9784998 | 20 | 0.00000951 | 0.015 | +− | HDL | 26 |
rs3211883 | 27 | 0.000298 | 0.007 | ++ | Obesity | 31 |
rs3211908 | 31 | 0.00212 | 0.0005 | ++ | Obesity | 31 |
rs1984112 | 35 | 0.00788 | 0.008 | +− | FFA | 29 |
rs2151916 | 43 | 0.0221 | 0.02 | +− | LDL | 28 |
SNP . | Rank* . | P† . | Lit P‡ . | Direction§ . | Phenotype . | Reference . |
---|---|---|---|---|---|---|
rs3211870 | 1 | 0.00000127 | 0.0079 | −+ | HDL | 26 |
rs3211870 | 1 | 0.00000127 | 0.005 | ++ | TMP | 27 |
rs3211849 | 3 | 0.00000172 | 0.029 | −+ | HDL | 26 |
rs7807607 | 5 | 0.00000211 | 0.07 | ++ | MS | 30 |
rs3211842 | 6 | 0.00000218 | 0.00074 | +− | HDL | 26 |
rs1358337 | 7 | 0.00000344 | 0.00066 | −+ | HDL | 26 |
rs1761667 | 8 | 0.00000417 | 0.00035 | ++ | TMP | 27 |
rs1761667 | 8 | 0.00000417 | 0.028 | +− | FFA | 29 |
rs1049654 | 10 | 0.00000560 | 0.0028 | −+ | HDL | 26 |
rs10499859 | 15 | 0.00000921 | 0.003 | − | TMP | 27 |
rs10499859 | 15 | 0.00000921 | 0.00028 | −+ | HDL | 26 |
rs3211867 | 19 | 0.00000951 | 0.003 | ++ | Obesity | 31 |
rs9784998 | 20 | 0.00000951 | 0.026 | ++ | TMP | 27 |
rs9784998 | 20 | 0.00000951 | 0.015 | +− | HDL | 26 |
rs3211883 | 27 | 0.000298 | 0.007 | ++ | Obesity | 31 |
rs3211908 | 31 | 0.00212 | 0.0005 | ++ | Obesity | 31 |
rs1984112 | 35 | 0.00788 | 0.008 | +− | FFA | 29 |
rs2151916 | 43 | 0.0221 | 0.02 | +− | LDL | 28 |
All SNPs from supplemental Table 1 with P < .05 from the white subset analysis ordered by P value.
TMP indicates total monocyte CD36 protein; MS, metabolic syndrome; and FFA, free fatty acids.
Rank indicates rank of SNP by P value in supplemental Table 1.
P value from supplemental Table 1.
Reported P value in study for association with phenotype.
Direction of SNP effect on CD36 expression, direction of SNP effect reported in study for association with phenotype.