Table 1
Demographic and clinical phenotypes of study populations used for assessment of platelet CD36 expression levels and genetic analyses
| Variable | Cardiac cath patients, n (%) | ASCLOGEN white patients, n (%) | ASCLOGEN black patients, n (%) |
|---|---|---|---|
| Age, y (mean ± SD) | 62 ± 9 | 63 ± 10 | 58 ± 9 |
| Sex | |||
| Male | 313 (62.7) | 304 (81.3) | 18 (72) |
| Female | 186 (37.3) | 70 (18.7) | 7 (28) |
| Tobacco use | |||
| Present | 62 (12.9) | 59 (15.8) | 9 (36) |
| Past | 338 (70.3) | 243 (65.0) | 20 (80) |
| History | |||
| Atherosclerosis | 271 (54.6) | 374 (100) | 25 (100) |
| MI | 249 (51.2) | 168 (44.9) | 13 (52) |
| CABG/PCI | 221 (44.3) | 235 (62.8) | 15 (60) |
| Stroke | 37 (9.8) | 18 (4.8) | 1 (4) |
| Hypertension BP > 120/90 mmHg | 412 (85.3) | 311 (83.2) | 23 (92) |
| Diabetes | 140 (29.4) | 111 (29.7) | 11 (44) |
| Serum cholesterol ≥ 200 mg/dL | 104 (23.4) | 57 (20.1) | 6 (31.6) |
| LDL ≥ 120 mg/dL | 86 (19.9) | 68 (23.9) | 6 (33.3) |
| HDL ≤ 50(M) or ≤ 60(F) mg/dL | 279 (63) | 221 (81.0) | 15 (88.2) |
| Triglyceride ≥ 200 mg/dL | 80 (18) | 65 (23.0) | 3 (15.8) |
| Glucose ≥ 120 mg/dL | 108 (23.6) | 85 (23.4) | 7 (29.2) |
Platelet count ≤ 150 ×103/ L | 37 (8.1) | 27 (7.3) | 1 (4.0) |
| BMI > 30 | 228 (44.3) | NA | NA |
| Variable | Cardiac cath patients, n (%) | ASCLOGEN white patients, n (%) | ASCLOGEN black patients, n (%) |
|---|---|---|---|
| Age, y (mean ± SD) | 62 ± 9 | 63 ± 10 | 58 ± 9 |
| Sex | |||
| Male | 313 (62.7) | 304 (81.3) | 18 (72) |
| Female | 186 (37.3) | 70 (18.7) | 7 (28) |
| Tobacco use | |||
| Present | 62 (12.9) | 59 (15.8) | 9 (36) |
| Past | 338 (70.3) | 243 (65.0) | 20 (80) |
| History | |||
| Atherosclerosis | 271 (54.6) | 374 (100) | 25 (100) |
| MI | 249 (51.2) | 168 (44.9) | 13 (52) |
| CABG/PCI | 221 (44.3) | 235 (62.8) | 15 (60) |
| Stroke | 37 (9.8) | 18 (4.8) | 1 (4) |
| Hypertension BP > 120/90 mmHg | 412 (85.3) | 311 (83.2) | 23 (92) |
| Diabetes | 140 (29.4) | 111 (29.7) | 11 (44) |
| Serum cholesterol ≥ 200 mg/dL | 104 (23.4) | 57 (20.1) | 6 (31.6) |
| LDL ≥ 120 mg/dL | 86 (19.9) | 68 (23.9) | 6 (33.3) |
| HDL ≤ 50(M) or ≤ 60(F) mg/dL | 279 (63) | 221 (81.0) | 15 (88.2) |
| Triglyceride ≥ 200 mg/dL | 80 (18) | 65 (23.0) | 3 (15.8) |
| Glucose ≥ 120 mg/dL | 108 (23.6) | 85 (23.4) | 7 (29.2) |
| Platelet count ≤ 150 ×103/L | 37 (8.1) | 27 (7.3) | 1 (4.0) |
| BMI > 30 | 228 (44.3) | NA | NA |
MI indicates myocardial infarction; CABG/PCI, coronary artery bypass graft/percutaneous coronary intervention; BP, blood pressure; BMI, body mass index; and NA, not applicable.