Table 1

Ten significantly up-regulated transcripts by LPS

SymbolGene full nameFold changePrimary function
Ptgs2 Prostaglandin 7.677 VEGF signaling pathway 
Cxcl 10 Chemokine (C-X-C motif) ligand 10 7.62 Immune response 
Nos 2 NO synthase 2, inducible, macrophage 6.331 Response to hypoxia 
Ligp 1 IFN-inducible GTPase 1 5.945 Cytokine and chemokine-mediated signaling pathway 
U90926 cDNA sequence U90926 5.878 Extracellular space 
Cxcl 11 Chemokine (C-X-C motif) ligand 11 5.639 Immune response 
Cxcl 1 Chemokine (C-X-C motif) ligand 1 5.432 Immune response 
CD69 CD69 Ag 5.351 Immune response 
Il6 Interleukin 6 5.33 Immune response 
Socs 3 Suppressor of cytokine signaling 3 5.149 Jak-STAT signaling pathway 
SymbolGene full nameFold changePrimary function
Ptgs2 Prostaglandin 7.677 VEGF signaling pathway 
Cxcl 10 Chemokine (C-X-C motif) ligand 10 7.62 Immune response 
Nos 2 NO synthase 2, inducible, macrophage 6.331 Response to hypoxia 
Ligp 1 IFN-inducible GTPase 1 5.945 Cytokine and chemokine-mediated signaling pathway 
U90926 cDNA sequence U90926 5.878 Extracellular space 
Cxcl 11 Chemokine (C-X-C motif) ligand 11 5.639 Immune response 
Cxcl 1 Chemokine (C-X-C motif) ligand 1 5.432 Immune response 
CD69 CD69 Ag 5.351 Immune response 
Il6 Interleukin 6 5.33 Immune response 
Socs 3 Suppressor of cytokine signaling 3 5.149 Jak-STAT signaling pathway 

Most significantly up-regulated mRNA transcripts by LPS. The top 10 most significantly up-regulated transcripts in response to LPS treatment as determined by Affymetrix microarrays. Data shown are the average values from 2 separate experiments.

LPS indicates lipopolysaccharide.

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