Pretreatment characteristics of MCL patients
| Study number . | Sex/age, y . | ALC, ×1000/μL . | Morphologic variant . | Lymphadenopathy . | Spleen size, cm* . | MIPI† . | IGHV gene . | % IgVH‡ . | CD38 MFI . |
|---|---|---|---|---|---|---|---|---|---|
| MCL 1 | M/65 | 26 | B | no | 20 | HR (6) | 1-08 | 96.3 | 2.4 |
| MCL 2 | F/49 | 20 | C | bulky | 32 | HR (6) | 4-04 | 99.7 | 151 |
| MCL 3 | M/66 | 17 | B | yes | 18 | HR (7) | 3-23 | 94.9 | 4.9 |
| MCL 4 | M/70 | 24 | B | yes | 18 | HR (9) | 1-08 | 98.6 | 35 |
| MCL 5 | M/51 | 6.8 | C | yes | 16 | IR (4) | 4-34 | 99.7 | 468 |
| MCL 6 | M/58 | 68 | C | no | 18 | IR (5) | 6-01 | 100 | 18 |
| MCL 7 | F/65 | 48 | C | yes | 10 | HR (7) | 3-07 | 100 | 69 |
| MCL 8 | M/69 | 11 | C | yes | 21 | IR (5) | 4-34 | 99 | 393 |
| MCL 9 | M/65 | 11 | C | yes | 21 | IR (5) | 3-11 | 100 | 93 |
| MCL10 | M/63 | 7.1 | C | yes | 11 | IR (4) | 1-18 | 98.6 | 222 |
| Study number . | Sex/age, y . | ALC, ×1000/μL . | Morphologic variant . | Lymphadenopathy . | Spleen size, cm* . | MIPI† . | IGHV gene . | % IgVH‡ . | CD38 MFI . |
|---|---|---|---|---|---|---|---|---|---|
| MCL 1 | M/65 | 26 | B | no | 20 | HR (6) | 1-08 | 96.3 | 2.4 |
| MCL 2 | F/49 | 20 | C | bulky | 32 | HR (6) | 4-04 | 99.7 | 151 |
| MCL 3 | M/66 | 17 | B | yes | 18 | HR (7) | 3-23 | 94.9 | 4.9 |
| MCL 4 | M/70 | 24 | B | yes | 18 | HR (9) | 1-08 | 98.6 | 35 |
| MCL 5 | M/51 | 6.8 | C | yes | 16 | IR (4) | 4-34 | 99.7 | 468 |
| MCL 6 | M/58 | 68 | C | no | 18 | IR (5) | 6-01 | 100 | 18 |
| MCL 7 | F/65 | 48 | C | yes | 10 | HR (7) | 3-07 | 100 | 69 |
| MCL 8 | M/69 | 11 | C | yes | 21 | IR (5) | 4-34 | 99 | 393 |
| MCL 9 | M/65 | 11 | C | yes | 21 | IR (5) | 3-11 | 100 | 93 |
| MCL10 | M/63 | 7.1 | C | yes | 11 | IR (4) | 1-18 | 98.6 | 222 |
C indicates classical; B, blastoid; HR, high risk; IR, intermediate risk; LR, low risk; MFI, mean fluorescence intensity; and MIPI, MCL international prognostic index.
Craniocaudal measurement on CT scan.
Simplified MIPI. Numeric score indicated in parentheses was calculated as described by Hoster et al.57
% Homology of IGHV gene to germline.