Table 3

HRs for HL from multivariable models

Adjusted HR (95% CI)
Model 1Model 2Model 3
Time-updated CD4 count, cells/μL    
    < 50 — 
    50-99 0.71 (0.19–2.67) — 0.89 (0.22–3.59) 
    100-199 0.80 (0.29–2.23) — 0.99 (0.31–3.10) 
    200-349 0.50 (0.18–1.35) — 0.57 (0.18–1.79) 
    At least 350 0.21 (0.08–0.59) — 0.27 (0.08–0.86) 
Time-update HIV-1 RNA, copies/mL    
    ≥ 100 000 — 
    10 000-99 999 — 1.63 (0.64–4.16) 2.06 (0.79–5.36) 
    501-9999 — 1.13 (0.41–3.06) 1.54 (0.55–4.32) 
    ≤ 500 — 0.67 (0.27–1.63) 0.98 (0.38–2.50) 
Adjusted HR (95% CI)
Model 1Model 2Model 3
Time-updated CD4 count, cells/μL    
    < 50 — 
    50-99 0.71 (0.19–2.67) — 0.89 (0.22–3.59) 
    100-199 0.80 (0.29–2.23) — 0.99 (0.31–3.10) 
    200-349 0.50 (0.18–1.35) — 0.57 (0.18–1.79) 
    At least 350 0.21 (0.08–0.59) — 0.27 (0.08–0.86) 
Time-update HIV-1 RNA, copies/mL    
    ≥ 100 000 — 
    10 000-99 999 — 1.63 (0.64–4.16) 2.06 (0.79–5.36) 
    501-9999 — 1.13 (0.41–3.06) 1.54 (0.55–4.32) 
    ≤ 500 — 0.67 (0.27–1.63) 0.98 (0.38–2.50) 

All models include patients before and after starting cART and adjusted for age, sex, transmission group, and CDC clinical stage. Model 1 additionally includes time-updated CD4 count, model 2 additionally includes time-updated HIV-1 RNA, and model 3 includes both time-updated CD4 count and HIV-1 RNA in addition to the baseline variables.

— indicates not applicable.

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