Table 1.

Biologic characteristics of the patient material


Patient

IgVH homology to germ line, %

ZAP-70

CD38

cDNA1*

CDS*

Cytogenetics
Mut-1   91.7   Positive   Negative   2.6   1.7   Not determined  
Mut-2   97.2   Negative   Negative   0.8   1.9   del 13q14  
Mut-3   91.1   Negative   Positive   0.3   0.4   trisomy 12, del 13q14  
No Mut-1   99.2   Positive   Positive   304.7   17.2   del 11q22  
No Mut-2   100   Positive   Positive   101.0   156.1   del 13q14  
No Mut-3
 
100
 
Positive
 
Positive
 
1023.0
 
389.9
 
Normal
 

Patient

IgVH homology to germ line, %

ZAP-70

CD38

cDNA1*

CDS*

Cytogenetics
Mut-1   91.7   Positive   Negative   2.6   1.7   Not determined  
Mut-2   97.2   Negative   Negative   0.8   1.9   del 13q14  
Mut-3   91.1   Negative   Positive   0.3   0.4   trisomy 12, del 13q14  
No Mut-1   99.2   Positive   Positive   304.7   17.2   del 11q22  
No Mut-2   100   Positive   Positive   101.0   156.1   del 13q14  
No Mut-3
 
100
 
Positive
 
Positive
 
1023.0
 
389.9
 
Normal
 

Fold up-regulation as compared to normal B cells.

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