Selected genes showing significant regulation in CD8+ DCs at 4 and 16 hours in response to IFN-γ
Probe ID . | Gene symbol . | Gene name . | Functional category . | Fold change, 4 h . | Fold change, 16 h . |
|---|---|---|---|---|---|
| 97731_at* | Indo | Indoleamine-pyrrole 2,3 dioxygenase | Tryptophan metabolism | +4.3 | –1.1 |
| 98606_s_at | Wars | Tryptophanyl-tRNA synthetase | Tryptophan metabolism | +3.5 | +2.6 |
| 101465_at | Stat1 | Signal transducer and activator of transcription 1 | Signal transduction; Transcription factor | +1.8 | +1.5 |
| 102401_at | Irf1 | IFN regulatory factor 1 | Transcription factor | +2.0 | +2.0 |
| 98002_at | Icsbp1 | IFN consensus sequence binding protein 1 | Transcription factor | +1.5 | +1.8 |
| 92832_at | Socs1 | Suppressor of cytokine signaling 1 | Signal transduction | +2.6 | +3.2 |
| 103486_15 | Il1b | IL-1β | Cytokine | –1.7 | –2.1 |
| 104388_at | Ccl9 | Chemokine (C-C motif) ligand 9 (MIP-1γ) | Chemokine | –1.6 | –4.6 |
| 102310_at | Ccl22 | Chemokine (C-C motif) ligand 22 (MDC;STCP-1;ABCD-1) | Chemokine | –1.2 | –1.6 |
| 101436_at | Cxcl9 | Chemokine (C-X-C motif) ligand 9 (MIG) | Chemokine | +27.8 | +22.6 |
| 93858_at | Cxcl10 | Chemokine (C-X-C motif) ligand 10 (IP-10) | Chemokine | +6.0 | +3.0 |
| 104354_at | Csf1r | Colony-stimulating factor 1 receptor | Cytokine receptor | –1.7 | –1.3 |
| 95295_at | Flt3 | FMS-like tyrosine kinase 3 | Cytokine receptor | –1.2 | –1.4 |
| 92689_at | Il18bp | IL-18 binding protein | Cytokine binding protein | +1.4 | +2.3 |
| 92962_at | Tnfrsf5 | Tumor necrosis factor receptor superfamily, member 5 (CD40) | Activating receptor | +1.6 | +1.3 |
| 98088_at | Cd14 | CD14 antigen | Activating receptor | –1.8 | –2.8 |
| 104023_at | Igsf7 | Immunoglobulin superfamily, member 7 (MAIR II) | Activating receptor | –2.0 | –1.8 |
| 100397_at | Tyrobp | TYRO protein tyrosine kinase binding protein (DAP12) | Adapter molecule | –1.3 | –1.3 |
| 95951_at | Clecsf8 | c-Type lectin, superfamily member 8 | Endocytic receptor | –1.6 | –2.0 |
| 96886_at | Stab1 | Stabilin 1 | Endocytic receptor | –1.5 | –2.0 |
| 100611_at | Lyzs | Lysozyme | APM | –1.6 | –1.7 |
| 103035_at | Tap1 | Transporter 1, ATP-binding cassette subfamily B | APM | +1.6 | +1.7 |
| 93085_at | Psmb9 | Proteasome subunit, β type 9 (Imp2) | APM | +1.3 | +1.4 |
| 101486_at | Psmb10 | Proteasome subunit, β type 10 (Imp10) | APM | +1.2 | +1.4 |
| 101019_at | Ctsc | Cathepsin C | APM | +1.4 | +1.4 |
| 101963_at | Ctsl | Cathepsin L | APM | –1.6 | –2.8 |
Probe ID . | Gene symbol . | Gene name . | Functional category . | Fold change, 4 h . | Fold change, 16 h . |
|---|---|---|---|---|---|
| 97731_at* | Indo | Indoleamine-pyrrole 2,3 dioxygenase | Tryptophan metabolism | +4.3 | –1.1 |
| 98606_s_at | Wars | Tryptophanyl-tRNA synthetase | Tryptophan metabolism | +3.5 | +2.6 |
| 101465_at | Stat1 | Signal transducer and activator of transcription 1 | Signal transduction; Transcription factor | +1.8 | +1.5 |
| 102401_at | Irf1 | IFN regulatory factor 1 | Transcription factor | +2.0 | +2.0 |
| 98002_at | Icsbp1 | IFN consensus sequence binding protein 1 | Transcription factor | +1.5 | +1.8 |
| 92832_at | Socs1 | Suppressor of cytokine signaling 1 | Signal transduction | +2.6 | +3.2 |
| 103486_15 | Il1b | IL-1β | Cytokine | –1.7 | –2.1 |
| 104388_at | Ccl9 | Chemokine (C-C motif) ligand 9 (MIP-1γ) | Chemokine | –1.6 | –4.6 |
| 102310_at | Ccl22 | Chemokine (C-C motif) ligand 22 (MDC;STCP-1;ABCD-1) | Chemokine | –1.2 | –1.6 |
| 101436_at | Cxcl9 | Chemokine (C-X-C motif) ligand 9 (MIG) | Chemokine | +27.8 | +22.6 |
| 93858_at | Cxcl10 | Chemokine (C-X-C motif) ligand 10 (IP-10) | Chemokine | +6.0 | +3.0 |
| 104354_at | Csf1r | Colony-stimulating factor 1 receptor | Cytokine receptor | –1.7 | –1.3 |
| 95295_at | Flt3 | FMS-like tyrosine kinase 3 | Cytokine receptor | –1.2 | –1.4 |
| 92689_at | Il18bp | IL-18 binding protein | Cytokine binding protein | +1.4 | +2.3 |
| 92962_at | Tnfrsf5 | Tumor necrosis factor receptor superfamily, member 5 (CD40) | Activating receptor | +1.6 | +1.3 |
| 98088_at | Cd14 | CD14 antigen | Activating receptor | –1.8 | –2.8 |
| 104023_at | Igsf7 | Immunoglobulin superfamily, member 7 (MAIR II) | Activating receptor | –2.0 | –1.8 |
| 100397_at | Tyrobp | TYRO protein tyrosine kinase binding protein (DAP12) | Adapter molecule | –1.3 | –1.3 |
| 95951_at | Clecsf8 | c-Type lectin, superfamily member 8 | Endocytic receptor | –1.6 | –2.0 |
| 96886_at | Stab1 | Stabilin 1 | Endocytic receptor | –1.5 | –2.0 |
| 100611_at | Lyzs | Lysozyme | APM | –1.6 | –1.7 |
| 103035_at | Tap1 | Transporter 1, ATP-binding cassette subfamily B | APM | +1.6 | +1.7 |
| 93085_at | Psmb9 | Proteasome subunit, β type 9 (Imp2) | APM | +1.3 | +1.4 |
| 101486_at | Psmb10 | Proteasome subunit, β type 10 (Imp10) | APM | +1.2 | +1.4 |
| 101019_at | Ctsc | Cathepsin C | APM | +1.4 | +1.4 |
| 101963_at | Ctsl | Cathepsin L | APM | –1.6 | –2.8 |