Table 2.

Thymocyte yield in TBI-conditioned recipients given different DBA/2 donor spleen cells 17 days after donor-cell injection


Donor cells

Recipient thymocyte yield, × 106
TBI conditioning only   24 ± 4  
Whole SPL*  6 ± 1.4  
CD4-SPL   59 ± 10  
B220-SPL   11 ± 4  
CD4-SPL + CD25CD4+ T  0.2 ± 0.06  
CD4-SPL + CD25CD4+ T + CD25+CD4+ T
 
35 ± 6
 

Donor cells

Recipient thymocyte yield, × 106
TBI conditioning only   24 ± 4  
Whole SPL*  6 ± 1.4  
CD4-SPL   59 ± 10  
B220-SPL   11 ± 4  
CD4-SPL + CD25CD4+ T  0.2 ± 0.06  
CD4-SPL + CD25CD4+ T + CD25+CD4+ T
 
35 ± 6
 

Data are mean ± SE; n = 8.

*

50 × 106 SPL cells/recipient

5 × 106 CD25CD4+ T cells/recipient

2.5 × 106 CD25+CD4+ T cells/recipient

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