Table 1.

Tissue Fe stores in MTf-/-mice compared with their MTf+/+littermates at 12 weeks of age on basal Fe (0.02% Fe/wt) and high-Fe (2.00% Fe/wt) diets


Fe diet and genotype by sex


Tissue Fe level (μg/g)*
n
Liver
Spleen
Heart
Kidney
0.02%      
    Male       
        MTf+/+  5   286 ± 14   2628 ± 223   454 ± 52   210 ± 7  
        MTf-/-  6   280 ± 34   3426 ± 398   481 ± 47   396 ± 114  
    Female       
        MTf+/+  6   552 ± 66   5565 ± 915   449 ± 43   374 ± 102  
        MTf-/-  6   451 ± 24   4949 ± 544   512 ± 34   361 ± 58  
2.00%      
    Male       
        MTf+/+  5   4018 ± 168   5274 ± 424   590 ± 51   466 ± 160  
        MTf-/-  6   3599 ± 378   4838 ± 365   702 ± 108   594 ± 164  
    Female       
        MTf+/+  6   4317 ± 184   8145 ± 554   683 ± 95   556 ± 129  
        MTf-/-
 
6
 
3872 ± 280
 
6701 ± 485
 
579 ± 35
 
468 ± 16
 

Fe diet and genotype by sex


Tissue Fe level (μg/g)*
n
Liver
Spleen
Heart
Kidney
0.02%      
    Male       
        MTf+/+  5   286 ± 14   2628 ± 223   454 ± 52   210 ± 7  
        MTf-/-  6   280 ± 34   3426 ± 398   481 ± 47   396 ± 114  
    Female       
        MTf+/+  6   552 ± 66   5565 ± 915   449 ± 43   374 ± 102  
        MTf-/-  6   451 ± 24   4949 ± 544   512 ± 34   361 ± 58  
2.00%      
    Male       
        MTf+/+  5   4018 ± 168   5274 ± 424   590 ± 51   466 ± 160  
        MTf-/-  6   3599 ± 378   4838 ± 365   702 ± 108   594 ± 164  
    Female       
        MTf+/+  6   4317 ± 184   8145 ± 554   683 ± 95   556 ± 129  
        MTf-/-
 
6
 
3872 ± 280
 
6701 ± 485
 
579 ± 35
 
468 ± 16
 
*

Values expressed as mean ± SEM.

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