Tissue Fe stores in MTf-/-mice compared with their MTf+/+littermates at 12 weeks of age on basal Fe (0.02% Fe/wt) and high-Fe (2.00% Fe/wt) diets
Fe diet and genotype by sex . | . | Tissue Fe level (μg/g)* . | . | . | . | |||
---|---|---|---|---|---|---|---|---|
. | n . | Liver . | Spleen . | Heart . | Kidney . | |||
0.02% | ||||||||
Male | ||||||||
MTf+/+ | 5 | 286 ± 14 | 2628 ± 223 | 454 ± 52 | 210 ± 7 | |||
MTf-/- | 6 | 280 ± 34 | 3426 ± 398 | 481 ± 47 | 396 ± 114 | |||
Female | ||||||||
MTf+/+ | 6 | 552 ± 66 | 5565 ± 915 | 449 ± 43 | 374 ± 102 | |||
MTf-/- | 6 | 451 ± 24 | 4949 ± 544 | 512 ± 34 | 361 ± 58 | |||
2.00% | ||||||||
Male | ||||||||
MTf+/+ | 5 | 4018 ± 168 | 5274 ± 424 | 590 ± 51 | 466 ± 160 | |||
MTf-/- | 6 | 3599 ± 378 | 4838 ± 365 | 702 ± 108 | 594 ± 164 | |||
Female | ||||||||
MTf+/+ | 6 | 4317 ± 184 | 8145 ± 554 | 683 ± 95 | 556 ± 129 | |||
MTf-/- | 6 | 3872 ± 280 | 6701 ± 485 | 579 ± 35 | 468 ± 16 |
Fe diet and genotype by sex . | . | Tissue Fe level (μg/g)* . | . | . | . | |||
---|---|---|---|---|---|---|---|---|
. | n . | Liver . | Spleen . | Heart . | Kidney . | |||
0.02% | ||||||||
Male | ||||||||
MTf+/+ | 5 | 286 ± 14 | 2628 ± 223 | 454 ± 52 | 210 ± 7 | |||
MTf-/- | 6 | 280 ± 34 | 3426 ± 398 | 481 ± 47 | 396 ± 114 | |||
Female | ||||||||
MTf+/+ | 6 | 552 ± 66 | 5565 ± 915 | 449 ± 43 | 374 ± 102 | |||
MTf-/- | 6 | 451 ± 24 | 4949 ± 544 | 512 ± 34 | 361 ± 58 | |||
2.00% | ||||||||
Male | ||||||||
MTf+/+ | 5 | 4018 ± 168 | 5274 ± 424 | 590 ± 51 | 466 ± 160 | |||
MTf-/- | 6 | 3599 ± 378 | 4838 ± 365 | 702 ± 108 | 594 ± 164 | |||
Female | ||||||||
MTf+/+ | 6 | 4317 ± 184 | 8145 ± 554 | 683 ± 95 | 556 ± 129 | |||
MTf-/- | 6 | 3872 ± 280 | 6701 ± 485 | 579 ± 35 | 468 ± 16 |
Values expressed as mean ± SEM.