Response rates at each time point*
| . | ≥ 65 y (115 pts), n (%) . | < 65 y (444 pts), n (%) . | P . |
|---|---|---|---|
| 3 mo | |||
| CHR | 111 (97) | 426 (96) | > .999 |
| 6 mo | |||
| CCyR | 79 (69) | 299 (67) | .82 |
| MMR | 54 (47) | 215 (48) | .83 |
| 12 mo | |||
| CCyR | 90 (78) | 343 (77) | .9 |
| MMR | 67 (58) | 262 (59) | .92 |
| 18 mo | |||
| CCyR | 85 (74) | 346 (78) | .38 |
| MMR | 65 (57) | 278 (63) | .24 |
| Cumulative incidence | |||
| CCyR | 100 (87) | 391 (88) | .75 |
| MMR | 98 (85) | 377 (85) | > .999 |
| . | ≥ 65 y (115 pts), n (%) . | < 65 y (444 pts), n (%) . | P . |
|---|---|---|---|
| 3 mo | |||
| CHR | 111 (97) | 426 (96) | > .999 |
| 6 mo | |||
| CCyR | 79 (69) | 299 (67) | .82 |
| MMR | 54 (47) | 215 (48) | .83 |
| 12 mo | |||
| CCyR | 90 (78) | 343 (77) | .9 |
| MMR | 67 (58) | 262 (59) | .92 |
| 18 mo | |||
| CCyR | 85 (74) | 346 (78) | .38 |
| MMR | 65 (57) | 278 (63) | .24 |
| Cumulative incidence | |||
| CCyR | 100 (87) | 391 (88) | .75 |
| MMR | 98 (85) | 377 (85) | > .999 |
No significant difference between older and younger patients was observed at any time point for complete hematologic response (CHR; time points after 3 months not shown), complete cytogenetic response (CCyR), and major molecular response (MMR) rates. The cumulative incidence of CCyR and MMR were similar in the 2 groups of age.
All analyses were performed according to the intention-to-treat principle.