Reduced expression of GPIX and GPIbα in Mks treated with QITP serum plus Qn
| Patient serum (dilution) . | −Qn . | +Qn . | ||||
|---|---|---|---|---|---|---|
| GPIIb+ . | GPIX+ . | GPIbα+ . | GPIIb+ . | GPIX+ . | GPIbα+ . | |
| WJ1 (1:5) | 97.8% | 89.0% | 55.7% | 96.5% | 39.9% | 11.7% |
| WJ2 (1:5) | 83.0% | 70.2% | 39.3% | 77.8% | 34.1% | 3.4% |
| NS (1:5) | ND | ND | ND | 94.9% | 91.7% | 57.0% |
| NS (1:5) | ND | ND | ND | 76.7% | 72.5% | 39.4% |
| Patient serum (dilution) . | −Qn . | +Qn . | ||||
|---|---|---|---|---|---|---|
| GPIIb+ . | GPIX+ . | GPIbα+ . | GPIIb+ . | GPIX+ . | GPIbα+ . | |
| WJ1 (1:5) | 97.8% | 89.0% | 55.7% | 96.5% | 39.9% | 11.7% |
| WJ2 (1:5) | 83.0% | 70.2% | 39.3% | 77.8% | 34.1% | 3.4% |
| NS (1:5) | ND | ND | ND | 94.9% | 91.7% | 57.0% |
| NS (1:5) | ND | ND | ND | 76.7% | 72.5% | 39.4% |
Percentage of positive cells for the indicated markers as determined by flow cytometry.
ND indicates not determined.