Novel miRNAs mapping to copy number alterations
| miRNA name . | Chromosome . | Bp start . | Bp end . | Deletion/amplification . | Mature miRNA sequence . | Target genes* . |
|---|---|---|---|---|---|---|
| miR-472 | 10 | 115 041 356 | 115 041 465 | Del | AAATGAATCATGTTGGGCCTGT | ADIPOQ |
| miR-463 | 10 | 103 351 146 | 103 351 255 | Del | AAGGGCTTCCTCTCTGCAGGAC | SYNGR1 |
| miR-431 | 13 | 49 468 528 | 49 468 637 | N | ACAAAAAAAAAAGCCCAACCCT | FOXK1, RELB, NF1 |
| miR-443 | 16 | 14 902 849 | 14 902 958 | N | AGAAGGGGTGAAATTTAAACGT | SYNGAP1 |
| miR-474 | 1 | 159 683 046 | 159 683 155 | Amp | AGCGGAACTTGAGGAGCCGAG | MEX3A |
| miR-460 | 4 | 153 629 916 | 153 630 025 | Del | AGCTTTTGGGAATTCAGGTAG | PTPRT |
| miR-468 | 11 | 61 032 625 | 61 032 734 | Amp | AGGGGGCGGGCTCCGGCG | ZNF385A, AAK1, NFIX |
| miR-478 | 2 | 96 827 730 | 96 827 839 | N | ATCAGGGCTTGTGGAATGGGAAG | ADAM11 |
| miR-432 | 19 | 6 367 420 | 6 367 529 | Amp | CAGCCCGGATCCCAGCCCACTTA | FBXL19 |
| miR-457 | 16 | 2 260 666 | 2 260 775 | N | CTCGTGGGCTCTGGCCACGGC | MN1 |
| miR-442 | 3 | 69 180 778 | 69 180 887 | Del | CTGACTGAATAGGTAGGGTCAT | CADM2 |
| miR-422 | 15 | 63 798 621 | 63 798 730 | Amp | GAAGAACTGTTGCATTTGCCC | MSL2L1, ERG, MPL, TRAF7 |
| miR-425 | 22 | 18 331 270 | 18 331 379 | Amp | GAGGGCATGCGCACTTTGTCC | RC3H1 |
| miR-427 | 3 | 50 687 498 | 50 687 607 | Del | GATGCGCCGCCCACTGCCCCGC | IMPAD1 |
| miR-437 | 2 | 207 356 179 | 207 356 288 | N | GCTGCACCGGAGACTGGGTAA | SP8, MAF, TET3 |
| miR-486 | 22 | 29 886 043 | 29 886 152 | Amp | GGAGGAACCTTGGAGCTTCGGC | SPTBN1, NFIX, NF2, ADAR |
| miR-418 | 19 | 12 675 394 | 12 675 503 | Amp | GTATTCGTACTGTCTGATGGG | |
| miR-416 | 2 | 12 256 683 | 12 256 792 | Del | TAGTGGATGATGCACTCTGTGC | ABCA5, JAK1 |
| miR-428 | 8 | 96 154 304 | 96 154 413 | Amp | TGAGGAGATCGTCGAGGTTGGC | LUZP1 |
| miR-419 | 16 | 1 724 971 | 1 725 080 | N | TGCACGGCACTGGGGACACGT | RELT |
| miR-404 | 16 | 14 912 572 | 14 912 681 | N | TGGGGCGGAGCTTCCGGAGGCC | TGRB1, NFIX |
| miR-408 | 16 | 84 505 724 | 84 505 833 | Del | TGGTGTGGAAGTCTAGGCCTG | FBXO41 |
| miR-481 | 7 | 29 686 866 | 29 686 975 | Del | TGTCTTACTCCCTCAGGCACAT | CUGBP2, MN1 |
| miR-450 | 9 | 136 881 134 | 136 881 243 | N | TGTGATATCATGGTTCCTGGGA | NLGN4X, ROCK1, ITCH |
| miR-402 | 9 | 96 888 098 | 96 888 207 | N | TGTTCCTGCTGAACTGAGCCAG | KLHL9, src |
| miR-421 | 19 | 12 912 277 | 12 912 386 | Amp | TTGGAGGGTGTGGAAGACATC | ACT1, SPARC |
| miR-414 | 19 | 764 560 | 764 669 | N | TTGGCCATGGGGCTGCGCGGGGC | KRAS |
| miRNA name . | Chromosome . | Bp start . | Bp end . | Deletion/amplification . | Mature miRNA sequence . | Target genes* . |
|---|---|---|---|---|---|---|
| miR-472 | 10 | 115 041 356 | 115 041 465 | Del | AAATGAATCATGTTGGGCCTGT | ADIPOQ |
| miR-463 | 10 | 103 351 146 | 103 351 255 | Del | AAGGGCTTCCTCTCTGCAGGAC | SYNGR1 |
| miR-431 | 13 | 49 468 528 | 49 468 637 | N | ACAAAAAAAAAAGCCCAACCCT | FOXK1, RELB, NF1 |
| miR-443 | 16 | 14 902 849 | 14 902 958 | N | AGAAGGGGTGAAATTTAAACGT | SYNGAP1 |
| miR-474 | 1 | 159 683 046 | 159 683 155 | Amp | AGCGGAACTTGAGGAGCCGAG | MEX3A |
| miR-460 | 4 | 153 629 916 | 153 630 025 | Del | AGCTTTTGGGAATTCAGGTAG | PTPRT |
| miR-468 | 11 | 61 032 625 | 61 032 734 | Amp | AGGGGGCGGGCTCCGGCG | ZNF385A, AAK1, NFIX |
| miR-478 | 2 | 96 827 730 | 96 827 839 | N | ATCAGGGCTTGTGGAATGGGAAG | ADAM11 |
| miR-432 | 19 | 6 367 420 | 6 367 529 | Amp | CAGCCCGGATCCCAGCCCACTTA | FBXL19 |
| miR-457 | 16 | 2 260 666 | 2 260 775 | N | CTCGTGGGCTCTGGCCACGGC | MN1 |
| miR-442 | 3 | 69 180 778 | 69 180 887 | Del | CTGACTGAATAGGTAGGGTCAT | CADM2 |
| miR-422 | 15 | 63 798 621 | 63 798 730 | Amp | GAAGAACTGTTGCATTTGCCC | MSL2L1, ERG, MPL, TRAF7 |
| miR-425 | 22 | 18 331 270 | 18 331 379 | Amp | GAGGGCATGCGCACTTTGTCC | RC3H1 |
| miR-427 | 3 | 50 687 498 | 50 687 607 | Del | GATGCGCCGCCCACTGCCCCGC | IMPAD1 |
| miR-437 | 2 | 207 356 179 | 207 356 288 | N | GCTGCACCGGAGACTGGGTAA | SP8, MAF, TET3 |
| miR-486 | 22 | 29 886 043 | 29 886 152 | Amp | GGAGGAACCTTGGAGCTTCGGC | SPTBN1, NFIX, NF2, ADAR |
| miR-418 | 19 | 12 675 394 | 12 675 503 | Amp | GTATTCGTACTGTCTGATGGG | |
| miR-416 | 2 | 12 256 683 | 12 256 792 | Del | TAGTGGATGATGCACTCTGTGC | ABCA5, JAK1 |
| miR-428 | 8 | 96 154 304 | 96 154 413 | Amp | TGAGGAGATCGTCGAGGTTGGC | LUZP1 |
| miR-419 | 16 | 1 724 971 | 1 725 080 | N | TGCACGGCACTGGGGACACGT | RELT |
| miR-404 | 16 | 14 912 572 | 14 912 681 | N | TGGGGCGGAGCTTCCGGAGGCC | TGRB1, NFIX |
| miR-408 | 16 | 84 505 724 | 84 505 833 | Del | TGGTGTGGAAGTCTAGGCCTG | FBXO41 |
| miR-481 | 7 | 29 686 866 | 29 686 975 | Del | TGTCTTACTCCCTCAGGCACAT | CUGBP2, MN1 |
| miR-450 | 9 | 136 881 134 | 136 881 243 | N | TGTGATATCATGGTTCCTGGGA | NLGN4X, ROCK1, ITCH |
| miR-402 | 9 | 96 888 098 | 96 888 207 | N | TGTTCCTGCTGAACTGAGCCAG | KLHL9, src |
| miR-421 | 19 | 12 912 277 | 12 912 386 | Amp | TTGGAGGGTGTGGAAGACATC | ACT1, SPARC |
| miR-414 | 19 | 764 560 | 764 669 | N | TTGGCCATGGGGCTGCGCGGGGC | KRAS |
Bp indicates base pair; Del, deletion; Amp, amplification; and N, copy number neutral.
Target Scan v5.1 was used to identify predicted target genes.