Clinical trials of interferon in myelofibrosis
| First author, year . | No. of patients . | Response rate, % . | Spleen size reduction, % of patients . | Discontinuation, % . | Type of IFN . |
|---|---|---|---|---|---|
| Hasselbalch, 1988 | 10 | 0 | 10 | NA | α2b |
| Barosi, 1989 | 10 | 25 | 0 | 25 | α2b |
| Gilbert, 1998 | 22 | NA | 58 | 46 | α2b |
| Tefferi, 2001 | 11 | 0 | 18 | 64 | α2 |
| Radin, 2003 | 31 | 3 | 33 | NA | α2 |
| Jabbour, 2007 | 11 | 9 | NA | 26 | peg-α2b |
| Ianotto, 2009 | 18 | 44 | 11 | 11 | peg-α2a |
| Silver, 2009 | 13 | 38 | 38 | 8 | α2b |
| First author, year . | No. of patients . | Response rate, % . | Spleen size reduction, % of patients . | Discontinuation, % . | Type of IFN . |
|---|---|---|---|---|---|
| Hasselbalch, 1988 | 10 | 0 | 10 | NA | α2b |
| Barosi, 1989 | 10 | 25 | 0 | 25 | α2b |
| Gilbert, 1998 | 22 | NA | 58 | 46 | α2b |
| Tefferi, 2001 | 11 | 0 | 18 | 64 | α2 |
| Radin, 2003 | 31 | 3 | 33 | NA | α2 |
| Jabbour, 2007 | 11 | 9 | NA | 26 | peg-α2b |
| Ianotto, 2009 | 18 | 44 | 11 | 11 | peg-α2a |
| Silver, 2009 | 13 | 38 | 38 | 8 | α2b |
For complete references, see supplemental Table 4.
IFN indicates interferon; and NA, data not available.