Table 1 Uses of interferon-α (alone or... | American Society of Hematology

Table 1

Uses of interferon-α (alone or in combination) for myeloid malignancies in 2011

Disease	Situation	Interferon use (+ combination)	Reference
Chronic myeloid leukemia	Chronic phase: Combined with imatinib as front line therapy Maintenance after imatinib plus interferon	Imatinib Interferon-α alone	Preudhomme et al⁴¹ Burchert et al³²
Systemic mast cell disease	Aggressive systemic mast cell disease (ASM)	Single agent	Kluin-Nelemans et al,⁷⁵ Lim et al⁷⁶
Myeloproliferative neoplasms	Polycythemia vera and essential thrombocythemia	Single agent	Quintas-Cardama et al,⁴⁶ Kiladjian et al⁷⁸
Hypereosinophilic syndrome	Resistance to steroids, hydroxyurea, and TKI-insensitive	Single agent	Butterfield and Gleich,⁹⁵ Ceretelli et al⁹⁶

Disease	Situation	Interferon use (+ combination)	Reference
Chronic myeloid leukemia	Chronic phase: Combined with imatinib as front line therapy Maintenance after imatinib plus interferon	Imatinib Interferon-α alone	Preudhomme et al⁴¹ Burchert et al³²
Systemic mast cell disease	Aggressive systemic mast cell disease (ASM)	Single agent	Kluin-Nelemans et al,⁷⁵ Lim et al⁷⁶
Myeloproliferative neoplasms	Polycythemia vera and essential thrombocythemia	Single agent	Quintas-Cardama et al,⁴⁶ Kiladjian et al⁷⁸
Hypereosinophilic syndrome	Resistance to steroids, hydroxyurea, and TKI-insensitive	Single agent	Butterfield and Gleich,⁹⁵ Ceretelli et al⁹⁶