Poor prognostic factors in relapsed or refractory Hodgkin lymphoma
| Patient group . | Factor . |
|---|---|
| Relapsed | Time to relapse < 1 year18,21-24 |
| Stage III-IV (IV: Lohri, Martin)18,19,21,22,24 | |
| Anemia18 | |
| B symptoms21,24 | |
| Poor performance status23 | |
| Refractory | Poor performance status17,23 |
| Age > 50 y17 | |
| Failure to attain a temporary remission17 | |
| B symptoms21 | |
| Stage III-IV (IV: Martin)19,21 | |
| ASCT | Previously untreated relapse23 |
| Response to chemotherapy19 | |
| Low serum albumin25 | |
| Anemia25 | |
| Age25 | |
| Lymphocytopenia25 | |
| B symptoms26 | |
| Extranodal disease26 | |
| Time to relapse < 1 year26 | |
| Disease status at ASCT20 | |
| Disease relapse in previous radiation field20 |
| Patient group . | Factor . |
|---|---|
| Relapsed | Time to relapse < 1 year18,21-24 |
| Stage III-IV (IV: Lohri, Martin)18,19,21,22,24 | |
| Anemia18 | |
| B symptoms21,24 | |
| Poor performance status23 | |
| Refractory | Poor performance status17,23 |
| Age > 50 y17 | |
| Failure to attain a temporary remission17 | |
| B symptoms21 | |
| Stage III-IV (IV: Martin)19,21 | |
| ASCT | Previously untreated relapse23 |
| Response to chemotherapy19 | |
| Low serum albumin25 | |
| Anemia25 | |
| Age25 | |
| Lymphocytopenia25 | |
| B symptoms26 | |
| Extranodal disease26 | |
| Time to relapse < 1 year26 | |
| Disease status at ASCT20 | |
| Disease relapse in previous radiation field20 |
ASCT indicates autologous stem cell transplant.