Table 2

Characterization of primary DLBCL cells

DLBCL PSTypeCD10Bcl-6IRF4/MUM-1NF-κB1/2
1 GCB + + + + 
2 GCB − + − + 
3 GCB + + N/A + 
4 GCB − + − + 
5 GCB + + N/A + 
6 GCB − + − + 
7 GCB + + − + 
8 GCB + + + + 
9 GCB + + + + 
10 ABC − − + + 
11 ABC − − + + 
12 ABC − − + + 
13 ABC − − + + 
14 ABC − − + + 
DLBCL PSTypeCD10Bcl-6IRF4/MUM-1NF-κB1/2
1 GCB + + + + 
2 GCB − + − + 
3 GCB + + N/A + 
4 GCB − + − + 
5 GCB + + N/A + 
6 GCB − + − + 
7 GCB + + − + 
8 GCB + + + + 
9 GCB + + + + 
10 ABC − − + + 
11 ABC − − + + 
12 ABC − − + + 
13 ABC − − + + 
14 ABC − − + + 

Fourteen DLBCL primary samples were used to characterize the expression of bcl-6, CD10, IRF-4 (MUM1), and NF-κB. CD10, bcl-6, and IRF-4 expression was analyzed using immunohistochemistry and Western blot analysis. NF-κB expression was analyzed by DNA-binding ELISA.

+ indicates positive; −, negative; and PS, patient samples.

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