Profile demonstrating the location of rearrangements in patients with detectable clonal Ig DNA
Patient no. . | IGH primers . | IGK primers . | |||||
---|---|---|---|---|---|---|---|
Fr1 . | Fr2 . | Fr3 . | DH1-6 . | DH7 . | Vk . | Kde . | |
1 | + | + | |||||
2 | + | + | |||||
4 | + | ||||||
6* | + | + | |||||
9 | + | + | + | + | |||
11 | + | ||||||
13 | + |
Patient no. . | IGH primers . | IGK primers . | |||||
---|---|---|---|---|---|---|---|
Fr1 . | Fr2 . | Fr3 . | DH1-6 . | DH7 . | Vk . | Kde . | |
1 | + | + | |||||
2 | + | + | |||||
4 | + | ||||||
6* | + | + | |||||
9 | + | + | + | + | |||
11 | + | ||||||
13 | + |
Fr indicates framework region; DH, diversity region; Vk, variable κ region; Kde, κ-deleting element (ie, λ restricted); +, present.
Fr3 screened alone for IgH.