Table 1

Demographics and baseline characteristics of patients with light-chain amyloidosis (AL)

CharacteristicValue
No. of patients 35 
Male/female* 24 (69)/11 (31) 
Age, y 64 (38-90) 
Clonality, λ* 26 (74) 
Number of organs involved*  
    1-2 23 (66) 
    3-4 12 (34) 
Kidney involvement* 30 (86) 
Heart involvement* 18 (51) 
Liver involvement* 5 (14) 
Peripheral nerve involvement* 9 (26) 
Serum albumin, g/dL 2.9 (1.0-5.7) 
Serum creatinine, mg/dL 1.3 (0.5-7.0) 
Serum alkaline phosphatase, IU/L 100 (49-459) 
β2-Microglobulin, mg/L 3.6 (1.3-15.0) 
Urine total protein, g/24 h 5.0 (0-45) 
Serum M-component, g/dL 0.7 (0-2.9) 
Urine M-component, g/24 h 0.2 (0-9.5) 
Serum free light chain, mg/L 159 (22-513) 
Serum cardiac troponin T, ng/mL 0.01 (0-0.3) 
NT-ProBNP, pg/mL 1773 (27-14 365) 
PCs by morphology 4.0 (0.1-24.0) 
PCs by MFC immunophenotyping 1.4 (0.1-15.0) 
CharacteristicValue
No. of patients 35 
Male/female* 24 (69)/11 (31) 
Age, y 64 (38-90) 
Clonality, λ* 26 (74) 
Number of organs involved*  
    1-2 23 (66) 
    3-4 12 (34) 
Kidney involvement* 30 (86) 
Heart involvement* 18 (51) 
Liver involvement* 5 (14) 
Peripheral nerve involvement* 9 (26) 
Serum albumin, g/dL 2.9 (1.0-5.7) 
Serum creatinine, mg/dL 1.3 (0.5-7.0) 
Serum alkaline phosphatase, IU/L 100 (49-459) 
β2-Microglobulin, mg/L 3.6 (1.3-15.0) 
Urine total protein, g/24 h 5.0 (0-45) 
Serum M-component, g/dL 0.7 (0-2.9) 
Urine M-component, g/24 h 0.2 (0-9.5) 
Serum free light chain, mg/L 159 (22-513) 
Serum cardiac troponin T, ng/mL 0.01 (0-0.3) 
NT-ProBNP, pg/mL 1773 (27-14 365) 
PCs by morphology 4.0 (0.1-24.0) 
PCs by MFC immunophenotyping 1.4 (0.1-15.0) 

NT-ProBNP indicates N-terminal prohormone of brain natriuretic peptide.

*

Results expressed as number (percentage) of cases.

Results expressed as median (range).

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