Growth inhibition of ATL cell lines induced by NK314 or etoposide
| Cell line . | IC50, nM . | |
|---|---|---|
| NK314 . | Etoposide . | |
| IL-2–independent | ||
| ATN-1 | 38.3 | 135.8 |
| MT-1 | 34.8 | 115.0 |
| ST1 | 45.2 | 138.0 |
| MT-2 | 22.6 | 76.7 |
| IL-2–dependent | ||
| KOB | 58.2 | 248.6 |
| ST1 (IL-2) | 71.3 | 214.5 |
| KK1 | 60.1 | 194.2 |
| OMT | 51.3 | 344.7 |
| MOLT4 | 32.6 | 157.9 |
| Jurkat | 29.2 | 145.8 |
| Normal PBMCs | ≥ 500 | ≥ 500 |
| Cell line . | IC50, nM . | |
|---|---|---|
| NK314 . | Etoposide . | |
| IL-2–independent | ||
| ATN-1 | 38.3 | 135.8 |
| MT-1 | 34.8 | 115.0 |
| ST1 | 45.2 | 138.0 |
| MT-2 | 22.6 | 76.7 |
| IL-2–dependent | ||
| KOB | 58.2 | 248.6 |
| ST1 (IL-2) | 71.3 | 214.5 |
| KK1 | 60.1 | 194.2 |
| OMT | 51.3 | 344.7 |
| MOLT4 | 32.6 | 157.9 |
| Jurkat | 29.2 | 145.8 |
| Normal PBMCs | ≥ 500 | ≥ 500 |