Table 3

P values of association of individual haplotypes in block 5 and 6 with VWF levels

HaplotypeFrequencyLog VWF value
Not ABO-adjustedABO-adjusted
Block 5-1 .23 1.7 × 10−8 .04 (.01) 7.8 × 10−10 .04 (.01) 
Block 5-2 .43 2.6 × 10−7 .03 (.01) 1.4 × 10−6 -.02 (.01) 
Block 5-3 .07 4.5 × 10−5 .04 (.01) 1.6 × 10−6 .05 (.01) 
Block 5-4 .08 5.9 × 10−12 -.07 (.01) 7 × 10−20 -.08 (.01) 
Block 5-5 .06 0.13 .02 (.01) 0.11 .02 (.01) 
Block 5-6 .04 1.7 × 10−6 .07 (.01) 4.7 × 10−6 .06 (.01) 
Block 5*  2.4 × 10−24 1.2 × 10−32 
Block 6-1 .28 .00076 .02 (.01) .00051 .02 (.01) 
Block 6-2 .61 .99 < .01 (.01) 0.21 .01 (.01) 
Block 6-3 .11 9 × 10−6 -.04 (.01) 4.9 × 10−11 -.05 (.01) 
Block 6*  2.6 × 10−6 4.6 × 10−11 
HaplotypeFrequencyLog VWF value
Not ABO-adjustedABO-adjusted
Block 5-1 .23 1.7 × 10−8 .04 (.01) 7.8 × 10−10 .04 (.01) 
Block 5-2 .43 2.6 × 10−7 .03 (.01) 1.4 × 10−6 -.02 (.01) 
Block 5-3 .07 4.5 × 10−5 .04 (.01) 1.6 × 10−6 .05 (.01) 
Block 5-4 .08 5.9 × 10−12 -.07 (.01) 7 × 10−20 -.08 (.01) 
Block 5-5 .06 0.13 .02 (.01) 0.11 .02 (.01) 
Block 5-6 .04 1.7 × 10−6 .07 (.01) 4.7 × 10−6 .06 (.01) 
Block 5*  2.4 × 10−24 1.2 × 10−32 
Block 6-1 .28 .00076 .02 (.01) .00051 .02 (.01) 
Block 6-2 .61 .99 < .01 (.01) 0.21 .01 (.01) 
Block 6-3 .11 9 × 10−6 -.04 (.01) 4.9 × 10−11 -.05 (.01) 
Block 6*  2.6 × 10−6 4.6 × 10−11 

In each cell of the 2 columns at right, the first row is the P value followed by the coefficient estimate (the increase of logVWF with 1 extra haplotype) and the corresponding SE.

*

The P value for the entire block instead of individual haplotypes in the block.

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