Table 1

Tryptase and MITF are coexpressed in patients with systemic mastocytosis and c-KIT mutations

Patient no.DiagnosisStaining
TryptaseMITF
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Systemic mastocytosis F522C ++ 
10 Aggressive systemic mastocytosis D816Y ++ − 
11 Aplastic anemia NT ++ − 
12 Aplastic anemia NT ++ − 
13 Aplastic anemia NT ++ − 
14 Aplastic anemia NT ++ − 
15 Aplastic anemia NT ++ − 
16 Aplastic anemia NT ++ − 
17 Aplastic anemia NT ++ − 
18 Fanconi anemia NT ++ − 
19 Acute lymphoblastic leukemia NT ++ − 
20 Hemophagocytic lymphohistiocytosis NT ++ − 
Patient no.DiagnosisStaining
TryptaseMITF
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Indolent systemic mastocytosis D816V ++ 
Systemic mastocytosis F522C ++ 
10 Aggressive systemic mastocytosis D816Y ++ − 
11 Aplastic anemia NT ++ − 
12 Aplastic anemia NT ++ − 
13 Aplastic anemia NT ++ − 
14 Aplastic anemia NT ++ − 
15 Aplastic anemia NT ++ − 
16 Aplastic anemia NT ++ − 
17 Aplastic anemia NT ++ − 
18 Fanconi anemia NT ++ − 
19 Acute lymphoblastic leukemia NT ++ − 
20 Hemophagocytic lymphohistiocytosis NT ++ − 

+ indicates positive staining ++, strongly positive staining −, no detectable staining and — NT, not tested.

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