Table 2 Univariate and multivariate... | American Society of Hematology

Table 2

Univariate and multivariate analysis (Cox model) of progression-free survival

	Univariate			Multivariate
	HR	95% CI	P	HR	95% CI	P
Response*			< .001			< .001
CR vs VGPR	0.16	0.10-0.24	< .001	0.22	0.13-0.38	< .001
CR vs PR	0.07	0.04-0.13	< .001	0.13	0.07-0.26	< .001
CR vs SD	0.03	0.01-0.05	< .001	0.06	0.03-0.12	< .001
CR vs PD	0.007	0.003-0.01	< .001	0.02	0.007-0.04	< .001
Age, y
> 75 vs ≤ 75	1.23	1.04-1.45	.014	1.14	0.93-1.40	.220
ISS			< .001			.016
II vs I	1.45	1.17-1.81	.001	1.36	1.06-1.74	.015
III vs I	1.59	1.24-2.03	< .001	1.47	1.12-1.95	.006
Durie and Salmon stage
III vs II	1.31	1.10-1.756	.003	1.33	1.08-1.63	.007
Therapy			< .001			< .001
MPT vs MP	0.70	0.59-0.84	< .001	0.78	0.63-0.98	.029
VMP vs MP	0.42	0.34-0.53	< .001	0.52	0.35-0.76	.001
VMPT-VT vs MP	0.27	0.21-0.36	< .001	0.51	0.35-0.75	.001

	Univariate			Multivariate
	HR	95% CI	P	HR	95% CI	P
Response*			< .001			< .001
CR vs VGPR	0.16	0.10-0.24	< .001	0.22	0.13-0.38	< .001
CR vs PR	0.07	0.04-0.13	< .001	0.13	0.07-0.26	< .001
CR vs SD	0.03	0.01-0.05	< .001	0.06	0.03-0.12	< .001
CR vs PD	0.007	0.003-0.01	< .001	0.02	0.007-0.04	< .001
Age, y
> 75 vs ≤ 75	1.23	1.04-1.45	.014	1.14	0.93-1.40	.220
ISS			< .001			.016
II vs I	1.45	1.17-1.81	.001	1.36	1.06-1.74	.015
III vs I	1.59	1.24-2.03	< .001	1.47	1.12-1.95	.006
Durie and Salmon stage
III vs II	1.31	1.10-1.756	.003	1.33	1.08-1.63	.007
Therapy			< .001			< .001
MPT vs MP	0.70	0.59-0.84	< .001	0.78	0.63-0.98	.029
VMP vs MP	0.42	0.34-0.53	< .001	0.52	0.35-0.76	.001
VMPT-VT vs MP	0.27	0.21-0.36	< .001	0.51	0.35-0.75	.001

SD indicates stable disease; and PD, progressive disease.

Treated as a time-dependent variable.