Summary of results for Campath in patients with LGL leukemia
| No. of patients . | Indication . | Response . | Duration of response . | Reference (year) . |
|---|---|---|---|---|
| 1 | Refractory patients: PRCA | 1 | 11 and 24 mo | 83 (2003) |
| 1 | Refractory patients: pancytopenia | 1 | 80 wk | 84 (2004) |
| 1 | PRCA | 1 | 6 mo | 85 (2005) |
| 1 | Refractory patients: PRCA | 1 | > 9 mo | 86 (2005) |
| 3 | 2 with pentostatin | 1/3 (1 death) | Short | 75 (2007) |
| 2 | — | 1 PR/2 | — | 87 (2009) |
| 2 | Refractory patients | 2/2 | 11 and 24 mo | 69 (2010) |
| 4 | Anemia/neutropenia | 1/4* | — | 12 (2010) |
| 8 | 5 patients; transfusion-dependent | 4/8 | NS | 13 (2009) |
| 1 | Refractory patient/neutropenia | Yes (molecular response) | > 12 mo | 88 (2010) |
| Total (n = 24) | 14/24 (58%) |
| No. of patients . | Indication . | Response . | Duration of response . | Reference (year) . |
|---|---|---|---|---|
| 1 | Refractory patients: PRCA | 1 | 11 and 24 mo | 83 (2003) |
| 1 | Refractory patients: pancytopenia | 1 | 80 wk | 84 (2004) |
| 1 | PRCA | 1 | 6 mo | 85 (2005) |
| 1 | Refractory patients: PRCA | 1 | > 9 mo | 86 (2005) |
| 3 | 2 with pentostatin | 1/3 (1 death) | Short | 75 (2007) |
| 2 | — | 1 PR/2 | — | 87 (2009) |
| 2 | Refractory patients | 2/2 | 11 and 24 mo | 69 (2010) |
| 4 | Anemia/neutropenia | 1/4* | — | 12 (2010) |
| 8 | 5 patients; transfusion-dependent | 4/8 | NS | 13 (2009) |
| 1 | Refractory patient/neutropenia | Yes (molecular response) | > 12 mo | 88 (2010) |
| Total (n = 24) | 14/24 (58%) |
PRCA indicates pure cell aplasia; —, not applicable; PR, partial response; and NS, not significant.
Two deaths of infection.