Table 1

Concentrations of PS that enhance the TFPI inhibition of FXa by 50% (EC50)

TFPI proteinEC50, nM
TFPIWT 8.0 ± 0.4 
TFPIC1 18.0 ± 1.8 
TFPIC2 12.9 ± 0.7 
TFPIC3 NM 
TFPIΔK3 NM 
TFPIK3P1 61.8 ± 13.4 
TFPI proteinEC50, nM
TFPIWT 8.0 ± 0.4 
TFPIC1 18.0 ± 1.8 
TFPIC2 12.9 ± 0.7 
TFPIC3 NM 
TFPIΔK3 NM 
TFPIK3P1 61.8 ± 13.4 

Data are from Figure 3B. Values are mean ± SEM.

PS indicates protein S; TFPI, tissue factor pathway inhibitor; and NM, not measurable.

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