One-year cumulative risk and rate ratio of a hospital contact (admission or hospital outpatient visit) involving infection among 407 patients with cITP and a comparison cohort of 4069 members of the general population in Denmark
| . | Patients with cITP, n (%) . | One-year risk among patients with cITP, % (95% CI) . | One-year risk among the comparison cohort, % (95% CI) . | Crude 1-year RR (95% CI) . | Adjusted 1-year RR (95% CI)* . |
|---|---|---|---|---|---|
| Total | 407 (100) | 15.3 (12.0-18.9) | 4.4 (3.8-5.1) | 3.9 (2.8-5.2) | 4.5 (3.3-6.1) |
| Age at cITP diagnosis, y | |||||
| ≤ 60 | 225 (55) | 8.9 (5.6-13.1) | 2.4 (1.8-3.1) | 3.9 (2.3-6.5) | 4.0 (2.4-6.8) |
| > 60 | 182 (45) | 23.1 (17.3-29.5) | 6.9 (5.8-8.1) | 4.1 (2.9-5.8) | 4.8 (3.3-6.9) |
| Sex | |||||
| Female | 254 (62) | 13.4 (9.5-17.9) | 4.3 (3.5-5.1) | 3.4 (2.3-5.0) | 3.8 (2.5-5.8) |
| Male | 153 (38) | 18.3 (12.7-24.8) | 4.6 (3.7-5.8) | 4.7 (3.0-7.5) | 5.8 (3.5-9.6) |
| Year of cITP diagnosis | |||||
| 1996-2001 | 167 (41) | 10.2 (6.2-15.3) | 3.2 (2.4-4.1) | 3.4 (2.0-5.9) | 3.8 (2.2-6.7) |
| 2002-2007 | 240 (59) | 18.8 (14.1-24.0) | 5.3 (4.4-6.2) | 4.1 (2.9-5.8) | 4.9 (3.4-6.9) |
| Comorbidity score | |||||
| 0 | 247 (61) | 8.5 (5.5-12.4) | 2.2 (1.6-2.8) | 4.2 (2.5-7.0) | 4.3 (2.6-7.1) |
| ≥ 1 | 160 (39) | 25.7 (19.2-32.6) | 7.9 (6.6-9.2) | 4.0 (2.8-5.6) | 4.7 (3.2-6.8) |
| . | Patients with cITP, n (%) . | One-year risk among patients with cITP, % (95% CI) . | One-year risk among the comparison cohort, % (95% CI) . | Crude 1-year RR (95% CI) . | Adjusted 1-year RR (95% CI)* . |
|---|---|---|---|---|---|
| Total | 407 (100) | 15.3 (12.0-18.9) | 4.4 (3.8-5.1) | 3.9 (2.8-5.2) | 4.5 (3.3-6.1) |
| Age at cITP diagnosis, y | |||||
| ≤ 60 | 225 (55) | 8.9 (5.6-13.1) | 2.4 (1.8-3.1) | 3.9 (2.3-6.5) | 4.0 (2.4-6.8) |
| > 60 | 182 (45) | 23.1 (17.3-29.5) | 6.9 (5.8-8.1) | 4.1 (2.9-5.8) | 4.8 (3.3-6.9) |
| Sex | |||||
| Female | 254 (62) | 13.4 (9.5-17.9) | 4.3 (3.5-5.1) | 3.4 (2.3-5.0) | 3.8 (2.5-5.8) |
| Male | 153 (38) | 18.3 (12.7-24.8) | 4.6 (3.7-5.8) | 4.7 (3.0-7.5) | 5.8 (3.5-9.6) |
| Year of cITP diagnosis | |||||
| 1996-2001 | 167 (41) | 10.2 (6.2-15.3) | 3.2 (2.4-4.1) | 3.4 (2.0-5.9) | 3.8 (2.2-6.7) |
| 2002-2007 | 240 (59) | 18.8 (14.1-24.0) | 5.3 (4.4-6.2) | 4.1 (2.9-5.8) | 4.9 (3.4-6.9) |
| Comorbidity score | |||||
| 0 | 247 (61) | 8.5 (5.5-12.4) | 2.2 (1.6-2.8) | 4.2 (2.5-7.0) | 4.3 (2.6-7.1) |
| ≥ 1 | 160 (39) | 25.7 (19.2-32.6) | 7.9 (6.6-9.2) | 4.0 (2.8-5.6) | 4.7 (3.2-6.8) |
cITP indicates chronic immune thrombocytopenia; CI, confidence interval; and RR, rate ratio.
Adjusted for age (≤ 60 y and > 60 y), sex, calendar year, and level of comorbidity.