Hemodynamic parameters of mice analyzed by intravital microscopy for Figure 3A
| . | WT + coIgG . | WT + anti-CD99 . | WT + anti-CD99L2 . | PECAM-1−/− + coIgG . | PECAM-1−/− + anti-CD99 . | PECAM-1−/− + anti-CD99L2 . |
|---|---|---|---|---|---|---|
| WBCs, ×106 cells/mL | 3.1 ± 0.4 | 3.5 ± 0.2 | 3.1 ± 0.4 | 4.9 ± 1.9 | 5.0 ± 1.3 | 3.7 ± 0.9 |
| Vessel diameter, μm | 28 ± 4 | 27 ± 2 | 26 ± 1 | 27 ± 1 | 27 ± 2 | 28 ± 3 |
| Wall shear rate, 1000 per second | 1.6 ± 0.3 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.7 ± 0.1 |
| . | WT + coIgG . | WT + anti-CD99 . | WT + anti-CD99L2 . | PECAM-1−/− + coIgG . | PECAM-1−/− + anti-CD99 . | PECAM-1−/− + anti-CD99L2 . |
|---|---|---|---|---|---|---|
| WBCs, ×106 cells/mL | 3.1 ± 0.4 | 3.5 ± 0.2 | 3.1 ± 0.4 | 4.9 ± 1.9 | 5.0 ± 1.3 | 3.7 ± 0.9 |
| Vessel diameter, μm | 28 ± 4 | 27 ± 2 | 26 ± 1 | 27 ± 1 | 27 ± 2 | 28 ± 3 |
| Wall shear rate, 1000 per second | 1.6 ± 0.3 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.7 ± 0.1 |
Data are mean ± SD (3-5 venules/mouse; n = 3-6).
WBCs indicates white blood cells.