Number of genes with altered expression after ECP
| Monocyte source . | Total . | Up-regulated . | Down-regulated . |
|---|---|---|---|
| Normal subjects (alone): N = 6 | 2820 | 1111 (39%) | 1709 (61%) |
| CTCL (alone): N = 3 | 3178 | 1956 (62%) | 1222 (38%) |
| GVHD (alone): N = 3 | 3235 | 2008 (62%) | 1227 (38%) |
| CTCL/GVHD (shared): N = 6 | 2532 | 1474 (58%) | 1058 (42%) |
| Normal/CTCL/GVHD (shared): N = 12 | 1129 | 498 (44%) | 631 (56%) |
| Monocyte source . | Total . | Up-regulated . | Down-regulated . |
|---|---|---|---|
| Normal subjects (alone): N = 6 | 2820 | 1111 (39%) | 1709 (61%) |
| CTCL (alone): N = 3 | 3178 | 1956 (62%) | 1222 (38%) |
| GVHD (alone): N = 3 | 3235 | 2008 (62%) | 1227 (38%) |
| CTCL/GVHD (shared): N = 6 | 2532 | 1474 (58%) | 1058 (42%) |
| Normal/CTCL/GVHD (shared): N = 12 | 1129 | 498 (44%) | 631 (56%) |
Number of genes significantly induced or suppressed by ECP. Activity of 1129 genes was similarly affected by ECP, in mononuclear cells procured from normal subjects and patients (CTCL and GVHD).