Table 3

The Flipf/d, LysMc/+ mice exhibit increased myeloid cytokines

CytokinesLittermate controls (pg/mL)Flipf/d, LysMc/+ (pg/mL)Mean fold increaseP
G-CSF 598.4 ± 213.1 8648.2 ± 1690.9 14.45 < .001 
IL-6 65.0 ± 39.4 1640.0 ± 464.4 25.23 < .001 
M-CSF 3.9 ± 0.54 11.4 ± 3.9 2.9 < .03 
GM-CSF 0.8 ± 0.8 21.7 ± 11.4 26.5 NS* 
IL-17 4.4 ± 1.0 14.9 ± 5.4 3.4 < .003 
CytokinesLittermate controls (pg/mL)Flipf/d, LysMc/+ (pg/mL)Mean fold increaseP
G-CSF 598.4 ± 213.1 8648.2 ± 1690.9 14.45 < .001 
IL-6 65.0 ± 39.4 1640.0 ± 464.4 25.23 < .001 
M-CSF 3.9 ± 0.54 11.4 ± 3.9 2.9 < .03 
GM-CSF 0.8 ± 0.8 21.7 ± 11.4 26.5 NS* 
IL-17 4.4 ± 1.0 14.9 ± 5.4 3.4 < .003 

n = 14 in each group.

*

NS indicates not significant.

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