Extramedullary hematopoiesis in the Flipf/d, LysMc/+ mice
| Colony-forming units . | Littermate controls (no. of colonies) . | Flipf/d, LysMc/+ (no. of colonies) . | P . |
|---|---|---|---|
| Granulocyte monocyte macrophage | |||
| Spleen | 5.8 ± 0.8 | 270.2 ± 36.1 | < .002 |
| Bone marrow | 92.3 ± 12.7 | 74.2 ± 14.4 | NS* |
| Megakaryocyte | |||
| Spleen | 1.8 ± 0.4 | 42.1 ± 0.9 | < .0001 |
| Bone marrow | 31.1 ± 4.2 | 21.4 ± 1.6 | NS* |
| Colony-forming units . | Littermate controls (no. of colonies) . | Flipf/d, LysMc/+ (no. of colonies) . | P . |
|---|---|---|---|
| Granulocyte monocyte macrophage | |||
| Spleen | 5.8 ± 0.8 | 270.2 ± 36.1 | < .002 |
| Bone marrow | 92.3 ± 12.7 | 74.2 ± 14.4 | NS* |
| Megakaryocyte | |||
| Spleen | 1.8 ± 0.4 | 42.1 ± 0.9 | < .0001 |
| Bone marrow | 31.1 ± 4.2 | 21.4 ± 1.6 | NS* |
Values represented are mean of 3 independent experiments using gender-matched littermate controls performed in triplicate.
NS, not significant.