Characteristics of the Australian PID cohort
| Characteristic . | No. of patients (%) . | Person-years follow-up for cancer . | |
|---|---|---|---|
| Total . | Mean (SD) . | ||
| Total | 1132 (100) | 18 055 | 16.0 (5.4) |
| Sex | |||
| Male | 604 (53.3) | 9219 | 15.3 (5.6) |
| Female | 528 (46.7) | 8836 | 16.7 (5.0) |
| PID classification* | |||
| Predominantly antibody deficiencies | 881 (77.8) | 14 313 | 16.2 (5.0) |
| Complement deficiencies | 78 (6.9) | 1298 | 16.6 (4.8) |
| Combined T-cell and B-cell immunodeficiencies | 54 (4.8) | 632 | 11.7 (7.2) |
| Other well-defined immunodeficiency syndromes | 66 (5.8) | 988 | 15.0 (6.9) |
| Congenital defects of phagocyte number, function, or both | 39 (3.5) | 602 | 15.4 (4.6) |
| Diseases of immune dysregulation | 14 (1.2) | 222 | 15.9 (4.5) |
| Age at follow-up for cancer, y | |||
| 0-9 | 552 (48.8) | 7748 | 14.0 (5.8) |
| 10-19 | 108 (9.5) | 1963 | 18.2 (4.2) |
| 20-29 | 133 (11.8) | 2490 | 18.7 (4.5) |
| 30-39 | 125 (11.0) | 2240 | 17.9 (4.5) |
| 40-49 | 102 (9.0) | 1697 | 16.6 (3.4) |
| 50-59 | 75 (6.6) | 1313 | 17.5 (3.8) |
| 60 and older | 37 (3.3) | 604 | 16.3 (3.0) |
| Characteristic . | No. of patients (%) . | Person-years follow-up for cancer . | |
|---|---|---|---|
| Total . | Mean (SD) . | ||
| Total | 1132 (100) | 18 055 | 16.0 (5.4) |
| Sex | |||
| Male | 604 (53.3) | 9219 | 15.3 (5.6) |
| Female | 528 (46.7) | 8836 | 16.7 (5.0) |
| PID classification* | |||
| Predominantly antibody deficiencies | 881 (77.8) | 14 313 | 16.2 (5.0) |
| Complement deficiencies | 78 (6.9) | 1298 | 16.6 (4.8) |
| Combined T-cell and B-cell immunodeficiencies | 54 (4.8) | 632 | 11.7 (7.2) |
| Other well-defined immunodeficiency syndromes | 66 (5.8) | 988 | 15.0 (6.9) |
| Congenital defects of phagocyte number, function, or both | 39 (3.5) | 602 | 15.4 (4.6) |
| Diseases of immune dysregulation | 14 (1.2) | 222 | 15.9 (4.5) |
| Age at follow-up for cancer, y | |||
| 0-9 | 552 (48.8) | 7748 | 14.0 (5.8) |
| 10-19 | 108 (9.5) | 1963 | 18.2 (4.2) |
| 20-29 | 133 (11.8) | 2490 | 18.7 (4.5) |
| 30-39 | 125 (11.0) | 2240 | 17.9 (4.5) |
| 40-49 | 102 (9.0) | 1697 | 16.6 (3.4) |
| 50-59 | 75 (6.6) | 1313 | 17.5 (3.8) |
| 60 and older | 37 (3.3) | 604 | 16.3 (3.0) |
PID indicates primary immune deficiency; and SD, standard deviation.
As classified by the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee.7