Table 2

Chromosomal abnormalities, overall and by race

Chromosomal abnormalitiesDS, no. (%)Non-DS, no. (%)P
ETV6-RUNX1    
    Overall 2/80 (2.5) 651/2710 (24.0) < .001 
    White 2/73 (2.7) 510/2068 (24.7) < .001 
    Other 0/7 (0) 141/642 (22.0) .356 
Trisomy 4 and 10    
    Overall 6/78 (7.7) 643/2689 (23.9) < .001 
    White 6/71 (8.4) 509/2051 (24.8) .001 
    Other 0/7 (0) 134/638 (21.0) .355 
TCF3-PBX1    
    Overall 3/80 (3.6) 123/2720 (4.3) .99 
    White 3/73 (4.1) 66/2076 (3.2) .507 
    Other 0/7 (0) 57/644 (8.8) > .999 
MLL    
    Overall 0/80 (0) 39/2729 (1.4) .627 
    White 0/73 (0) 29/2085 (1.4) .623 
    Other 0/7 (0) 10/644 (1.6) > .999 
BCR-ABL1    
    Overall 0/79 (0) 57/2668 (2.1) .408 
    White 0/72 (0) 42/2032 (2.1) .399 
    Other 0/7 (0) 15/636 (2.4) > .999 
Chromosomal abnormalitiesDS, no. (%)Non-DS, no. (%)P
ETV6-RUNX1    
    Overall 2/80 (2.5) 651/2710 (24.0) < .001 
    White 2/73 (2.7) 510/2068 (24.7) < .001 
    Other 0/7 (0) 141/642 (22.0) .356 
Trisomy 4 and 10    
    Overall 6/78 (7.7) 643/2689 (23.9) < .001 
    White 6/71 (8.4) 509/2051 (24.8) .001 
    Other 0/7 (0) 134/638 (21.0) .355 
TCF3-PBX1    
    Overall 3/80 (3.6) 123/2720 (4.3) .99 
    White 3/73 (4.1) 66/2076 (3.2) .507 
    Other 0/7 (0) 57/644 (8.8) > .999 
MLL    
    Overall 0/80 (0) 39/2729 (1.4) .627 
    White 0/73 (0) 29/2085 (1.4) .623 
    Other 0/7 (0) 10/644 (1.6) > .999 
BCR-ABL1    
    Overall 0/79 (0) 57/2668 (2.1) .408 
    White 0/72 (0) 42/2032 (2.1) .399 
    Other 0/7 (0) 15/636 (2.4) > .999 

Total number varies for each abnormality depending on the number of cases with missing data.

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