Results of multivariate analysis of age, cytogenetic risk group, and SNP 6.0 array-based lesion cutoffs on overall survival in AML
| Variable . | All-treatment group (n = 114) . | Intensive-treatment group (n = 97) . | ||||
|---|---|---|---|---|---|---|
| Hazard ratio . | CI . | P . | Hazard ratio . | CI . | P . | |
| Age ≥ 60 vs < 60 | 2.60 | 1.54-4.41 | < .01 | 2.48 | 1.38-4.44 | < .01 |
| Cytogenetic risk group unfavorable vs not | 1.93 | 1.10-3.39 | .02 | 1.84 | 0.97-3.49 | .06 |
| No. of SNP array genomic lesions ≥ 2 vs < 2 | 2.26 | 1.27-4.05 | < .01 | 2.10 | 1.08-4.08 | .03 |
| Age ≥ 60 vs < 60 | 2.67 | 1.57-4.53 | < .01 | 2.58 | 1.44-4.61 | < .01 |
| Cytogenetic risk group unfavorable vs not | 1.94 | 1.06-3.55 | .03 | 1.86 | 0.94-3.7 | .07 |
| No. of SNP array genomic lesions ≥ 3 vs < 3 | 2.07 | 1.11-3.88 | .02 | 1.96 | 0.95-4.01 | .06 |
| Age ≥ 60 vs < 60 | 3.13 | 1.89-5.2 | < .01 | 3.17 | 1.84-5.47 | < .01 |
| Cytogenetic risk group unfavorable vs not | 2.27 | 1.33-3.88 | < .01 | 2.26 | 1.26-4.05 | .01 |
| No. of SNP array genomic lesions ≥ 4 vs < 4 | 2.28 | 1.28-4.06 | < .01 | 2.37 | 1.25-4.49 | .01 |
| Variable . | All-treatment group (n = 114) . | Intensive-treatment group (n = 97) . | ||||
|---|---|---|---|---|---|---|
| Hazard ratio . | CI . | P . | Hazard ratio . | CI . | P . | |
| Age ≥ 60 vs < 60 | 2.60 | 1.54-4.41 | < .01 | 2.48 | 1.38-4.44 | < .01 |
| Cytogenetic risk group unfavorable vs not | 1.93 | 1.10-3.39 | .02 | 1.84 | 0.97-3.49 | .06 |
| No. of SNP array genomic lesions ≥ 2 vs < 2 | 2.26 | 1.27-4.05 | < .01 | 2.10 | 1.08-4.08 | .03 |
| Age ≥ 60 vs < 60 | 2.67 | 1.57-4.53 | < .01 | 2.58 | 1.44-4.61 | < .01 |
| Cytogenetic risk group unfavorable vs not | 1.94 | 1.06-3.55 | .03 | 1.86 | 0.94-3.7 | .07 |
| No. of SNP array genomic lesions ≥ 3 vs < 3 | 2.07 | 1.11-3.88 | .02 | 1.96 | 0.95-4.01 | .06 |
| Age ≥ 60 vs < 60 | 3.13 | 1.89-5.2 | < .01 | 3.17 | 1.84-5.47 | < .01 |
| Cytogenetic risk group unfavorable vs not | 2.27 | 1.33-3.88 | < .01 | 2.26 | 1.26-4.05 | .01 |
| No. of SNP array genomic lesions ≥ 4 vs < 4 | 2.28 | 1.28-4.06 | < .01 | 2.37 | 1.25-4.49 | .01 |