SNP 6.0 array-based lesion thresholds and associated CR/CRi rates in AML
SNP 6.0 array lesion threshold . | Proportion of CR/CRi in low lesion group . | Proportion of CR/CRi in high lesion group . | Z-score for log-odds ratio . | P . |
---|---|---|---|---|
All treatment | ||||
0 vs ≥ 1 | 0.8 | 0.507 | 2.95 | .003 |
≤ 1 vs ≥ 2 | 0.729 | 0.415 | 3.21 | .001 |
≤ 2 vs ≥ 3 | 0.722 | 0.344 | 3.56 | < .001 |
≤ 3 vs ≥ 4 | 0.708 | 0.227 | 3.77 | < .001 |
≤ 4 vs ≥ 5 | 0.703 | 0.2 | 3.72 | < .001 |
Intensive chemo only | ||||
0 vs ≥ 1 | 0.857 | 0.574 | 2.73 | .006 |
≤ 1 vs ≥ 2 | 0.774 | 0.5 | 2.72 | .007 |
≤ 2 vs ≥ 3 | 0.771 | 0.423 | 3.19 | .002 |
≤ 3 vs ≥ 4 | 0.759 | 0.294 | 3.41 | .001 |
≤ 4 vs ≥ 5 | 0.753 | 0.267 | 3.93 | .001 |
SNP 6.0 array lesion threshold . | Proportion of CR/CRi in low lesion group . | Proportion of CR/CRi in high lesion group . | Z-score for log-odds ratio . | P . |
---|---|---|---|---|
All treatment | ||||
0 vs ≥ 1 | 0.8 | 0.507 | 2.95 | .003 |
≤ 1 vs ≥ 2 | 0.729 | 0.415 | 3.21 | .001 |
≤ 2 vs ≥ 3 | 0.722 | 0.344 | 3.56 | < .001 |
≤ 3 vs ≥ 4 | 0.708 | 0.227 | 3.77 | < .001 |
≤ 4 vs ≥ 5 | 0.703 | 0.2 | 3.72 | < .001 |
Intensive chemo only | ||||
0 vs ≥ 1 | 0.857 | 0.574 | 2.73 | .006 |
≤ 1 vs ≥ 2 | 0.774 | 0.5 | 2.72 | .007 |
≤ 2 vs ≥ 3 | 0.771 | 0.423 | 3.19 | .002 |
≤ 3 vs ≥ 4 | 0.759 | 0.294 | 3.41 | .001 |
≤ 4 vs ≥ 5 | 0.753 | 0.267 | 3.93 | .001 |