Risk of myocardial infarction with increasing quartiles of t-PA
| . | Q1 . | Q2 . | Q3 . | Q4 . |
|---|---|---|---|---|
| Cutoff, ng/mL | 6.3 | 8.1 | 10.6 | |
| No. of patients | 104 | 104 | 185 | 160 |
| No. of control subjects | 158 | 159 | 159 | 158 |
| Model 1: age, OR (95% CI) | 1 | 1.1 (0.8-1.5) | 2.0 (1.4-2.7) | 1.7 (1.2-2.4) |
| Model 2: model 1 + HDL and total cholesterol, triglycerides, BMI, and diabetes, OR (95% CI) | 1 | 0.9 (0.6-1.3) | 1.5 (1.1-2.2) | 1.1 (0.8-1.6) |
| Model 3: model 2 + CRP, VWF, systolic and diastolic blood pressures, OR (95% CI) | 1 | 0.9 (0.6-1.4) | 1.4 (1.0-2.0) | 1.0 (0.7-1.5) |
| Model 4: model 3 + PAI-1 | 1 | 0.9 (0.6-1.3) | 1.4 (1.0-2.0) | 1.0 (0.6-1.5) |
| . | Q1 . | Q2 . | Q3 . | Q4 . |
|---|---|---|---|---|
| Cutoff, ng/mL | 6.3 | 8.1 | 10.6 | |
| No. of patients | 104 | 104 | 185 | 160 |
| No. of control subjects | 158 | 159 | 159 | 158 |
| Model 1: age, OR (95% CI) | 1 | 1.1 (0.8-1.5) | 2.0 (1.4-2.7) | 1.7 (1.2-2.4) |
| Model 2: model 1 + HDL and total cholesterol, triglycerides, BMI, and diabetes, OR (95% CI) | 1 | 0.9 (0.6-1.3) | 1.5 (1.1-2.2) | 1.1 (0.8-1.6) |
| Model 3: model 2 + CRP, VWF, systolic and diastolic blood pressures, OR (95% CI) | 1 | 0.9 (0.6-1.4) | 1.4 (1.0-2.0) | 1.0 (0.7-1.5) |
| Model 4: model 3 + PAI-1 | 1 | 0.9 (0.6-1.3) | 1.4 (1.0-2.0) | 1.0 (0.6-1.5) |
t-PA levels were missing for 1 control subject and 2 patients.
t-PA indicates tissue plasminogen activator; Q, quartile; HDL, high-density lipoprotein; BMI, body mass index; CRP, C-reactive protein; VWF, von Willebrand factor; PAI-1, plasminogen activator inhibitor 1.