Table 1

Definitions of pain-related terminology

TermDefinition
Nociception The neural processes of encoding and processing noxious stimuli 
Nociceptors A receptor on primary afferent fibers preferentially sensitive to a noxious stimulus or to a stimulus that would become noxious if prolonged 
Hyperalgesia An increase in pain to a stimulus that is normally painful 
Allodynia Pain evoked by a stimulus that does not normally provoke pain 
Central sensitization Enhanced excitability of nociceptive neurons in the dorsal horn of spinal cord resulting from tissue damage or inflammation 
Neuropathic pain Pain initiated or caused by a primary lesion or dysfunction in the nervous system 
Nocifensive behavior Behavioral responses to noxious stimuli 
TermDefinition
Nociception The neural processes of encoding and processing noxious stimuli 
Nociceptors A receptor on primary afferent fibers preferentially sensitive to a noxious stimulus or to a stimulus that would become noxious if prolonged 
Hyperalgesia An increase in pain to a stimulus that is normally painful 
Allodynia Pain evoked by a stimulus that does not normally provoke pain 
Central sensitization Enhanced excitability of nociceptive neurons in the dorsal horn of spinal cord resulting from tissue damage or inflammation 
Neuropathic pain Pain initiated or caused by a primary lesion or dysfunction in the nervous system 
Nocifensive behavior Behavioral responses to noxious stimuli 

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