Treatment-emergent AEs of any grade (all cycles)
| AEs, total N = 302, 26 patients . | Number . | Percentage . |
|---|---|---|
| Any | 100 | |
| Hematologic | 95 | 31 |
| Neutropenia | 29 | |
| Anemia | 30 | |
| Thrombocytopenia | 21 | |
| Lymphopenia | 14 | |
| Eosinophilia | 1 | |
| Gastrointestinal | 49 | 16 |
| Nausea | 39 | |
| Constipation | 5 | |
| Diarrhea | 5 | |
| Dry mouth | 3 | |
| Abdominal distension | 3 | |
| General disorders | 37 | 12 |
| Fatigue | 15 | |
| Anorexia | 4 | |
| Pyrexia | 4 | |
| Asthenia | 14 | |
| Dermatologic | 29 | 10 |
| Skin rash | 11 | |
| Pruritis | 3 | |
| Skin atrophy | 5 | |
| Dry skin | 1 | |
| Hyperpigmentation | 9 | |
| Cardiovascular | 22 | 7 |
| Left ventricular systolic dysfunction | 6 | |
| Peripheral edema | 6 | |
| Hypotension | 5 | |
| Atrial fibrillation | 1 | |
| Thrombosis | 2 | |
| Cardiac ischemia | 2 | |
| Infectious | 19 | 6 |
| Others | 51 | 17 |
| AEs, total N = 302, 26 patients . | Number . | Percentage . |
|---|---|---|
| Any | 100 | |
| Hematologic | 95 | 31 |
| Neutropenia | 29 | |
| Anemia | 30 | |
| Thrombocytopenia | 21 | |
| Lymphopenia | 14 | |
| Eosinophilia | 1 | |
| Gastrointestinal | 49 | 16 |
| Nausea | 39 | |
| Constipation | 5 | |
| Diarrhea | 5 | |
| Dry mouth | 3 | |
| Abdominal distension | 3 | |
| General disorders | 37 | 12 |
| Fatigue | 15 | |
| Anorexia | 4 | |
| Pyrexia | 4 | |
| Asthenia | 14 | |
| Dermatologic | 29 | 10 |
| Skin rash | 11 | |
| Pruritis | 3 | |
| Skin atrophy | 5 | |
| Dry skin | 1 | |
| Hyperpigmentation | 9 | |
| Cardiovascular | 22 | 7 |
| Left ventricular systolic dysfunction | 6 | |
| Peripheral edema | 6 | |
| Hypotension | 5 | |
| Atrial fibrillation | 1 | |
| Thrombosis | 2 | |
| Cardiac ischemia | 2 | |
| Infectious | 19 | 6 |
| Others | 51 | 17 |