Selection of patients for transplantation
Good-risk candidates |
Young age |
No comorbid conditions |
No active infections |
Lymphohematopoietic disease in remission or responsive to therapy |
Good socioeconomic support system |
HLA-matched donor |
Low risk of posttransplantation relapse |
High-risk candidates |
Older age |
Comorbid conditions present |
Refractory/relapsed disease (diagnosis-dependent) |
Aggressive prior therapy |
High-risk/complex karyotype |
Good-risk candidates |
Young age |
No comorbid conditions |
No active infections |
Lymphohematopoietic disease in remission or responsive to therapy |
Good socioeconomic support system |
HLA-matched donor |
Low risk of posttransplantation relapse |
High-risk candidates |
Older age |
Comorbid conditions present |
Refractory/relapsed disease (diagnosis-dependent) |
Aggressive prior therapy |
High-risk/complex karyotype |