Table 4

Cryoglobulin composition before and after PIRR or Peg-IFN-α/RBV therapy in 10 partially responsive patients who reached sustained HCV clearance

ParameterCryoprecipitate
Before, n = 10After, n = 10
HCV RNA, IU/mL 1 710 466 ± 644 019 < detection limit 
IgM, mg/L 7136 ± 3590 5856 ± 5640 
IgG, mg/L 206 ± 97 188 ± 36 
C3, mg/dL 16.2 ± 11.0 8 ± 5.3 
C4, mg/dL 1.5 ± 0.6 2.4 ± 2.1 
C1q, mg/dL 2.9 ± 1.3 3.2 ± 1.1 
RF activity, IU/mL 606.7 ± 233 404 ± 186.4 
Anti-HCV antibody titer, sample/negative ratio 88 ± 26 52 ± 31 
ParameterCryoprecipitate
Before, n = 10After, n = 10
HCV RNA, IU/mL 1 710 466 ± 644 019 < detection limit 
IgM, mg/L 7136 ± 3590 5856 ± 5640 
IgG, mg/L 206 ± 97 188 ± 36 
C3, mg/dL 16.2 ± 11.0 8 ± 5.3 
C4, mg/dL 1.5 ± 0.6 2.4 ± 2.1 
C1q, mg/dL 2.9 ± 1.3 3.2 ± 1.1 
RF activity, IU/mL 606.7 ± 233 404 ± 186.4 
Anti-HCV antibody titer, sample/negative ratio 88 ± 26 52 ± 31 
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