Table 1

Clinical characteristics of all patients and patients from major subtypes

All (n = 320)ALK+ (n = 78)ALK− (n = 113)PTCLU (n = 70)AITL (n = 28)Other (n = 31)
Sex       
    Male 197 (61.6%) 44 (56.4%) 69 (61.1%) 49 (70.0%) 15 (53.6%) 20 (64.5%) 
    Female 123 (38.4%) 34 (43.6%) 44 (38.9%) 21 (30.0%) 13 (46.4%) 11 (35.5%) 
Median age, y (range) 50 (18, 78) 37 (18, 74) 50 (18, 77) 54 (20, 78) 64 (22, 77) 49 (18, 75) 
Age > 60 y 96 (30.0%) 11 (14.1%) 39 (34.5%) 25 (35.7%) 15 (53.6%) 6 (19.4%) 
LDH > UNV 121 (37.8%) 21 (26.9%) 41 (36.3%) 31 (44.3%) 19 (67.9%) 9 (29.0%) 
ECOG > 1 53 (16.6%) 11 (14.1%) 16 (14.2%) 12 (17.1%) 8 (28.6%) 6 (19.4%) 
Stage III, IV 163 (50.9%) 41 (52.6%) 49 (43.4%) 37 (52.9%) 23 (82.1%) 13 (41.9%) 
More than 1 extranodal site 61 (19.1%) 16 (20.5%) 16 (14.2%) 18 (25.7%) 3 (10.7%) 8 (25.8%) 
IPI       
    0, 1 163 (50.9%) 45 (57.7%) 64 (56.6%) 32 (45.7%) 6 (21.4%) 16 (51.6%) 
    2 80 (25.0%) 21 (26.9%) 27 (23.9%) 16 (22.9%) 8 (28.6%) 8 (25.8%) 
    3 48 (15.0%) 10 (12.8%) 14 (12.4%) 12 (17.1%) 7 (25.0%) 5 (16.1%) 
    4, 5 29 (9.1%) 2 (2.6%) 8 (7.1%) 10 (14.3%) 7 (25.0%) 2 (6.5%) 
B symptoms 139 (43.4%) 42 (53.8%) 39 (34.5%) 28 (40.0%) 19 (67.9%) 11 (35.5%) 
Bulky disease 82 (25.6%) 23 (29.5%) 35 (31.0%) 12 (17.1%) 2 (7.1%) 10 (32.3%) 
All (n = 320)ALK+ (n = 78)ALK− (n = 113)PTCLU (n = 70)AITL (n = 28)Other (n = 31)
Sex       
    Male 197 (61.6%) 44 (56.4%) 69 (61.1%) 49 (70.0%) 15 (53.6%) 20 (64.5%) 
    Female 123 (38.4%) 34 (43.6%) 44 (38.9%) 21 (30.0%) 13 (46.4%) 11 (35.5%) 
Median age, y (range) 50 (18, 78) 37 (18, 74) 50 (18, 77) 54 (20, 78) 64 (22, 77) 49 (18, 75) 
Age > 60 y 96 (30.0%) 11 (14.1%) 39 (34.5%) 25 (35.7%) 15 (53.6%) 6 (19.4%) 
LDH > UNV 121 (37.8%) 21 (26.9%) 41 (36.3%) 31 (44.3%) 19 (67.9%) 9 (29.0%) 
ECOG > 1 53 (16.6%) 11 (14.1%) 16 (14.2%) 12 (17.1%) 8 (28.6%) 6 (19.4%) 
Stage III, IV 163 (50.9%) 41 (52.6%) 49 (43.4%) 37 (52.9%) 23 (82.1%) 13 (41.9%) 
More than 1 extranodal site 61 (19.1%) 16 (20.5%) 16 (14.2%) 18 (25.7%) 3 (10.7%) 8 (25.8%) 
IPI       
    0, 1 163 (50.9%) 45 (57.7%) 64 (56.6%) 32 (45.7%) 6 (21.4%) 16 (51.6%) 
    2 80 (25.0%) 21 (26.9%) 27 (23.9%) 16 (22.9%) 8 (28.6%) 8 (25.8%) 
    3 48 (15.0%) 10 (12.8%) 14 (12.4%) 12 (17.1%) 7 (25.0%) 5 (16.1%) 
    4, 5 29 (9.1%) 2 (2.6%) 8 (7.1%) 10 (14.3%) 7 (25.0%) 2 (6.5%) 
B symptoms 139 (43.4%) 42 (53.8%) 39 (34.5%) 28 (40.0%) 19 (67.9%) 11 (35.5%) 
Bulky disease 82 (25.6%) 23 (29.5%) 35 (31.0%) 12 (17.1%) 2 (7.1%) 10 (32.3%) 

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