Demographic and baseline features of patients enrolled in the AIDA-0493 and AIDA-2000 trials
| Characteristic . | Median (range) . | AIDA-0493 (n = 642) . | Median (range) . | AIDA-2000 (n = 453) . | P . |
|---|---|---|---|---|---|
| Sex | |||||
| Male | — | 349 (54.4%) | — | 229 (50.5%) | .1089 |
| Female | — | 293 (45.6%) | — | 224 (49.5%) | |
| Age, y | 38.2 (18.0-60.7) | — | 40.9 (18.0-61.0) | — | .0193 |
| WBC count, ×109/L | 2.8 (0.3-570.0) | — | 2.3 (0.3-770.0) | — | .3494 |
| Platelet count, ×109/L | 24.0 (1.0-241.0) | — | 24.0 (0.5-264.0) | — | .8165 |
| PML/RARA isoform | |||||
| Bcr1 | — | 321 (56.4%) | — | 191 (54.2%) | |
| Bcr2 | — | 43 (7.6%) | — | 33 (9.4%) | |
| Bcr3 | — | 205 (36.0%) | — | 128 (36.4%) | |
| Unknown | — | 73 | — | 101 | .5889 |
| Relapse risk | |||||
| Low | — | 130 (20.4%) | — | 116 (25.6%) | |
| Intermediate | — | 331 (52.0%) | — | 208 (45.9%) | |
| High | — | 176 (27.6%) | — | 129 (28.5%) | |
| Unknown | — | 5 | — | 0 | .0744 |
| Characteristic . | Median (range) . | AIDA-0493 (n = 642) . | Median (range) . | AIDA-2000 (n = 453) . | P . |
|---|---|---|---|---|---|
| Sex | |||||
| Male | — | 349 (54.4%) | — | 229 (50.5%) | .1089 |
| Female | — | 293 (45.6%) | — | 224 (49.5%) | |
| Age, y | 38.2 (18.0-60.7) | — | 40.9 (18.0-61.0) | — | .0193 |
| WBC count, ×109/L | 2.8 (0.3-570.0) | — | 2.3 (0.3-770.0) | — | .3494 |
| Platelet count, ×109/L | 24.0 (1.0-241.0) | — | 24.0 (0.5-264.0) | — | .8165 |
| PML/RARA isoform | |||||
| Bcr1 | — | 321 (56.4%) | — | 191 (54.2%) | |
| Bcr2 | — | 43 (7.6%) | — | 33 (9.4%) | |
| Bcr3 | — | 205 (36.0%) | — | 128 (36.4%) | |
| Unknown | — | 73 | — | 101 | .5889 |
| Relapse risk | |||||
| Low | — | 130 (20.4%) | — | 116 (25.6%) | |
| Intermediate | — | 331 (52.0%) | — | 208 (45.9%) | |
| High | — | 176 (27.6%) | — | 129 (28.5%) | |
| Unknown | — | 5 | — | 0 | .0744 |
— indicates not applicable.