Table 1

The QUORUM statement on how to report a systematic review

Heading/subheadingDescriptor
Title Can clearly determine that report is a systematic review. 
Abstract Uses a structured format. 
    Objectives Describes clinical question explicitly. 
    Data sources Lists the databases used and other sources of data. 
    Review methods Describes the process of how data was selection, quality assessment, data extraction, and any meta-analysis performed. 
    Results Describes included and excluded studies and the results of any meta-analysis. 
    Conclusion Describes the main results. 
Introduction Discusses the clinical problem, why the intervention may work, and the reasons for performing the review. 
Methods  
    Searching Describes the data sources (eg, databases, handsearching, registers, researchers) and any search exclusions (date, language). 
    Selection Inclusion and exclusion criteria outlined. 
    Validity assessment Describes how any quality assessment was performed. 
    Data abstraction Discusses how data was extracted from studies. 
    Quantitative data synthesis Information on how data was combined (meta-analysis), including statistical methods used, measures of effect, and any sensitivity and subgroup analysis performed. Also explains which tests were performed, looking for heterogeneity and publication bias. 
Results  
    Trial flow Provides a figure showing the number of studies screened, included, and excluded at each step. 
    Study characteristics Each trial is described briefly, including participant demographics, number of participants, intervention, and follow-up. 
    Quantitative data synthesis Presents simple summary results for individual studies and any meta-analysis performed. 
Discussion Discusses the answer to the original question in the light of the best available evidence and any possible biases. Also suggests future research. 
Heading/subheadingDescriptor
Title Can clearly determine that report is a systematic review. 
Abstract Uses a structured format. 
    Objectives Describes clinical question explicitly. 
    Data sources Lists the databases used and other sources of data. 
    Review methods Describes the process of how data was selection, quality assessment, data extraction, and any meta-analysis performed. 
    Results Describes included and excluded studies and the results of any meta-analysis. 
    Conclusion Describes the main results. 
Introduction Discusses the clinical problem, why the intervention may work, and the reasons for performing the review. 
Methods  
    Searching Describes the data sources (eg, databases, handsearching, registers, researchers) and any search exclusions (date, language). 
    Selection Inclusion and exclusion criteria outlined. 
    Validity assessment Describes how any quality assessment was performed. 
    Data abstraction Discusses how data was extracted from studies. 
    Quantitative data synthesis Information on how data was combined (meta-analysis), including statistical methods used, measures of effect, and any sensitivity and subgroup analysis performed. Also explains which tests were performed, looking for heterogeneity and publication bias. 
Results  
    Trial flow Provides a figure showing the number of studies screened, included, and excluded at each step. 
    Study characteristics Each trial is described briefly, including participant demographics, number of participants, intervention, and follow-up. 
    Quantitative data synthesis Presents simple summary results for individual studies and any meta-analysis performed. 
Discussion Discusses the answer to the original question in the light of the best available evidence and any possible biases. Also suggests future research. 

Modified from Moher et al.

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