Table 2

Risk stratification according to cytogenetics in 408 patients from the study cohort according to Grimwade23,24 

Refined Medical Research Council criteria23,24 No. of cases (%)
Intermediate risk group 366 (89.7) 
    Normal karyotype 281 (68.9) 
    Other non-complex 85 (20.8) 
Adverse risk group 42 (10.3) 
    Complex alterations 21 (5.1) 
    −7/add(7q) 11 (2.7) 
    del(5q)/−5/add(5q) 6 (1.5) 
    Others* 4 (1.0) 
Total* 408 (100) 
Refined Medical Research Council criteria23,24 No. of cases (%)
Intermediate risk group 366 (89.7) 
    Normal karyotype 281 (68.9) 
    Other non-complex 85 (20.8) 
Adverse risk group 42 (10.3) 
    Complex alterations 21 (5.1) 
    −7/add(7q) 11 (2.7) 
    del(5q)/−5/add(5q) 6 (1.5) 
    Others* 4 (1.0) 
Total* 408 (100) 
*

Cases with “others” were represented by deletions, other aberrations, and cases with independent clones as classified according to Medical Research Council criteria.

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