Clinical features of patients with hematologic manifestations with or without APS
| . | Clinical APS, n = 25 . | Nonclinical APS, n = 30 . | P . |
|---|---|---|---|
| Mean age, y ± SD | 41.8 ± 12 | 38.8 ± 13 | NS |
| Females | 22 (88) | 22 (73) | NS |
| Median follow-up, y (range) | 13.2 ± 8.4 (1.4-37) | 5.4 ± 5.8 (0.14-24) | .001 |
| Thrombocytopenia | 18 (72) | 17 (57) | NS |
| Hemolytic anemia | 5 (20) | 9 (30) | |
| Evans syndrome | 2 (8) | 4(13) | |
| Overall response to treatment at LMA | 24 (96) | 25 (83) | NS |
| Relapse | 13 (52) | 14 (46) | NS |
| Prednisone use | 19 (76) | 25 (83) | NS |
| Immunosuppresor use | 14 (56) | 20 (66) | NS |
| Aspirin use | 20 (80) | 24 (80) | NS |
| Splenectomy | 8 (32) | 8 (26) | NS |
| Basal platelet count, n (range) | 36 000 (1000-98 000) | 16 500 (2000-98 000) | NS |
| Platelet count at LMA, n (range) | 244 500 (31 000-309 000) | 136 133 (29 000-329 000) | .01 |
| Basal hemoglobin, n (range) | 6.8 (2-10.4) | 6.4 (3.9-10.7) | NS |
| Hemoglobin at LMA, n (range) | 14.3 (11.8-17) | 14(10.8-16.4) | NS |
| . | Clinical APS, n = 25 . | Nonclinical APS, n = 30 . | P . |
|---|---|---|---|
| Mean age, y ± SD | 41.8 ± 12 | 38.8 ± 13 | NS |
| Females | 22 (88) | 22 (73) | NS |
| Median follow-up, y (range) | 13.2 ± 8.4 (1.4-37) | 5.4 ± 5.8 (0.14-24) | .001 |
| Thrombocytopenia | 18 (72) | 17 (57) | NS |
| Hemolytic anemia | 5 (20) | 9 (30) | |
| Evans syndrome | 2 (8) | 4(13) | |
| Overall response to treatment at LMA | 24 (96) | 25 (83) | NS |
| Relapse | 13 (52) | 14 (46) | NS |
| Prednisone use | 19 (76) | 25 (83) | NS |
| Immunosuppresor use | 14 (56) | 20 (66) | NS |
| Aspirin use | 20 (80) | 24 (80) | NS |
| Splenectomy | 8 (32) | 8 (26) | NS |
| Basal platelet count, n (range) | 36 000 (1000-98 000) | 16 500 (2000-98 000) | NS |
| Platelet count at LMA, n (range) | 244 500 (31 000-309 000) | 136 133 (29 000-329 000) | .01 |
| Basal hemoglobin, n (range) | 6.8 (2-10.4) | 6.4 (3.9-10.7) | NS |
| Hemoglobin at LMA, n (range) | 14.3 (11.8-17) | 14(10.8-16.4) | NS |
Values are number (percentage) unless stated otherwise.
APS indicates antiphospholipid syndrome; LMA, last medical appointment; and NS, not significant.