Changes in mineral parameters from iron overload
| FTIRI parameter . | Category . | Placebo . | Iron dextran . | P . |
|---|---|---|---|---|
| Cortical bone | Mineral-to-matrix | 7.7 ± 0.4 | 6.3 ± 0.7 | .002 |
| Carbonate-to-mineral | 0.0074 ± 0.0003 | 0.006 ± 0.001 | .01 | |
| Carbonate-to-matrix | 0.057 ± 0.004 | 0.038 ± 0.009 | .001 | |
| Cross-link | 3.4 ± 0.36 | 3.3 ± 0.36 | NS | |
| Crystallinity | 1.12 ± 0.015 | 1.10 ± 0.03 | .01 | |
| Trabecular bone | Mineral-to-matrix | 4.0 ± 0.5 | 3.5 ± 0.2 | .06 |
| Carbonate-to-mineral | 0.0046 ± 0.001 | 0.0030 ± 0.001 | .01 | |
| Carbonate-to-matrix | 0.019 ± 0.006 | 0.010 ± 0.0001 | .01 | |
| Cross-link | 3.1 ± 0.37 | 3.4 ± 0.4 | NS | |
| Crystallinity | 1.054 ± 0.014 | 1.050 ± 0.01 | NS | |
| X-ray diffraction | Crystal size, nm | 13.5 ± 4.6 | 18 ± 5.4 | NS |
| FTIRI parameter . | Category . | Placebo . | Iron dextran . | P . |
|---|---|---|---|---|
| Cortical bone | Mineral-to-matrix | 7.7 ± 0.4 | 6.3 ± 0.7 | .002 |
| Carbonate-to-mineral | 0.0074 ± 0.0003 | 0.006 ± 0.001 | .01 | |
| Carbonate-to-matrix | 0.057 ± 0.004 | 0.038 ± 0.009 | .001 | |
| Cross-link | 3.4 ± 0.36 | 3.3 ± 0.36 | NS | |
| Crystallinity | 1.12 ± 0.015 | 1.10 ± 0.03 | .01 | |
| Trabecular bone | Mineral-to-matrix | 4.0 ± 0.5 | 3.5 ± 0.2 | .06 |
| Carbonate-to-mineral | 0.0046 ± 0.001 | 0.0030 ± 0.001 | .01 | |
| Carbonate-to-matrix | 0.019 ± 0.006 | 0.010 ± 0.0001 | .01 | |
| Cross-link | 3.1 ± 0.37 | 3.4 ± 0.4 | NS | |
| Crystallinity | 1.054 ± 0.014 | 1.050 ± 0.01 | NS | |
| X-ray diffraction | Crystal size, nm | 13.5 ± 4.6 | 18 ± 5.4 | NS |
Values are mean ± SD.
NS indicates not significant.