Micro-CT analysis of mice treated with placebo, high-dose iron dextran (1 g/kg per week), and low-dose iron dextran (0.1 g/kg per week)
| . | Placebo . | High-dose iron . | Low-dose iron . |
|---|---|---|---|
| Trabecular bone | |||
| BMD, mg/mm3 | 841.63 ± 11.42 | 832.38 ± 19 | 822 ± 8.05 |
| BVF, percentage | 19.79 ± 3.6 | 11.21 ± 2.9* | 13.7 ± 1.9‡ |
| Trabecular number, N/mm | 4.93 ± 0.334 | 3.94 ± 0.568* | 4.46 ± 0.16‡ |
| Trabecular thickness, μm | 48.836 ± 4.9 | 43.566 ± 4.8† | 45.37 ± 4.48‡ |
| Trabecular spacing, μm | 190.04 ± 14.15 | 254.62 ± 41* | 215.825 ± 8.3‡ |
| Cortical bone | |||
| Cortical thickness, mm | 0.192 ± 0.0064 | 0.151 ± 0.0002* | 0.17 ± 0.00738‡ |
| Inner perimeter, mm | 3.44 ± 0.38 | 4.02 ± 0.045 | 3.84 ± 0.3 |
| Outer perimeter, mm | 5.10 ± 0.36 | 5.21 ± 0.764 | 5.14 ± 0.328 |
| Cortical area, mm2 | 0.9117 ± 0.1 | 0.769 ± 0.0592* | 0.864 ± 0.04437‡ |
| Marrow area, mm2 | 1.06 ± 0.1774 | 1.1885 ± 0.08† | 1.14 ± 0.159‡ |
| . | Placebo . | High-dose iron . | Low-dose iron . |
|---|---|---|---|
| Trabecular bone | |||
| BMD, mg/mm3 | 841.63 ± 11.42 | 832.38 ± 19 | 822 ± 8.05 |
| BVF, percentage | 19.79 ± 3.6 | 11.21 ± 2.9* | 13.7 ± 1.9‡ |
| Trabecular number, N/mm | 4.93 ± 0.334 | 3.94 ± 0.568* | 4.46 ± 0.16‡ |
| Trabecular thickness, μm | 48.836 ± 4.9 | 43.566 ± 4.8† | 45.37 ± 4.48‡ |
| Trabecular spacing, μm | 190.04 ± 14.15 | 254.62 ± 41* | 215.825 ± 8.3‡ |
| Cortical bone | |||
| Cortical thickness, mm | 0.192 ± 0.0064 | 0.151 ± 0.0002* | 0.17 ± 0.00738‡ |
| Inner perimeter, mm | 3.44 ± 0.38 | 4.02 ± 0.045 | 3.84 ± 0.3 |
| Outer perimeter, mm | 5.10 ± 0.36 | 5.21 ± 0.764 | 5.14 ± 0.328 |
| Cortical area, mm2 | 0.9117 ± 0.1 | 0.769 ± 0.0592* | 0.864 ± 0.04437‡ |
| Marrow area, mm2 | 1.06 ± 0.1774 | 1.1885 ± 0.08† | 1.14 ± 0.159‡ |