Patient and donor characteristics (n = 40)
Characteristic . | Value . |
---|---|
Median patient age, y (range) | 37 (7-63) |
Median donor age, y (range) | 35 (6-63) |
Patient sex, male/female | 23/17 |
Donor sex, male/female | 27/13 |
Diagnosis, no. (%) | |
Chronic myeloid leukemia, chronic phase | 3 (7.5) |
Acute myeloid leukemia | 10 (25) |
Acute lymphoblastic leukemia | 7 (17.5) |
Myelodysplasia | 3 (7.5) |
Non-Hodgkin lymphoma | 6 (15) |
Hodgkin lymphoma | 1 (2.5) |
Multiple myeloma | 4 (10) |
Aplastic anemia | 4 (10) |
FasL deficiency | 1 (2.5) |
β-Thalassemia | 1 (2.5) |
Type of transplantation, no. (%) | |
Matched sibling | 23 (57.5) |
Matched unrelated | 15 (37.5) |
Mismatched unrelated | 2 (5) |
Reduced-intensity conditioning | 14 |
T-cell depletion, ex vivo | 9 |
Stem cell source, no. (%) | |
Bone marrow | 17 (42.5) |
Peripheral blood | 23 (57.5) |
CMV serology, donor/patient, no. (%) | |
D+/P− | 4 (10) |
D+/P+ | 14 (35) |
D−/P− | 20 (50) |
D−/P+ | 2 (5) |
Characteristic . | Value . |
---|---|
Median patient age, y (range) | 37 (7-63) |
Median donor age, y (range) | 35 (6-63) |
Patient sex, male/female | 23/17 |
Donor sex, male/female | 27/13 |
Diagnosis, no. (%) | |
Chronic myeloid leukemia, chronic phase | 3 (7.5) |
Acute myeloid leukemia | 10 (25) |
Acute lymphoblastic leukemia | 7 (17.5) |
Myelodysplasia | 3 (7.5) |
Non-Hodgkin lymphoma | 6 (15) |
Hodgkin lymphoma | 1 (2.5) |
Multiple myeloma | 4 (10) |
Aplastic anemia | 4 (10) |
FasL deficiency | 1 (2.5) |
β-Thalassemia | 1 (2.5) |
Type of transplantation, no. (%) | |
Matched sibling | 23 (57.5) |
Matched unrelated | 15 (37.5) |
Mismatched unrelated | 2 (5) |
Reduced-intensity conditioning | 14 |
T-cell depletion, ex vivo | 9 |
Stem cell source, no. (%) | |
Bone marrow | 17 (42.5) |
Peripheral blood | 23 (57.5) |
CMV serology, donor/patient, no. (%) | |
D+/P− | 4 (10) |
D+/P+ | 14 (35) |
D−/P− | 20 (50) |
D−/P+ | 2 (5) |
D indicates donor; and P, patient.