Clinical characteristics of the SLE patients according to ACR criteria and presence of cardiovascular events at any time during disease
. | Cohort I (n = 10) . | Cohort II (n = 69) . |
---|---|---|
Malar rash, % | 30 | 61 |
Discoid rash, % | 20 | 30 |
Photosensitivity, % | 40 | 64 |
Oral ulcers, % | 10 | 30 |
Arthritis, % | 50 | 81 |
Serositis, % | 40 | 65 |
Renal disease, % | 50 | 42 |
Neurologic disorder, % | 10 | 9 |
Hematologic manifestations, % | 70 | 52 |
Leukopenia, % | 70 | 39 |
Lymphopenia, % | 60 | 28 |
Thrombocytopenia, % | 20 | 20 |
Immunology, % | 80 | 67 |
ANA, % | 100 | 100 |
Anti-DNA antibodies, % | 90 | 71 |
Anti-cardiolipin antibodies, % | 50 | 45 |
Anti-phospholipid antibody syndrome, % | 20 | 29 |
Vascular disease, % | 10 | 45 |
Median time since event, y (range) | 24 | 8 (2-36) |
Venous thrombosis, % | 10 | 29 |
Median time since event, y (range) | 24 | 16 (3-36) |
Arterial thrombosis, % | 0 | 19 |
Median time since event, y (range) | 8 (1-18) | |
Myocardial infarction, % | 0 | 15 |
Median time since event, y (range) | 7 (2-30) |
. | Cohort I (n = 10) . | Cohort II (n = 69) . |
---|---|---|
Malar rash, % | 30 | 61 |
Discoid rash, % | 20 | 30 |
Photosensitivity, % | 40 | 64 |
Oral ulcers, % | 10 | 30 |
Arthritis, % | 50 | 81 |
Serositis, % | 40 | 65 |
Renal disease, % | 50 | 42 |
Neurologic disorder, % | 10 | 9 |
Hematologic manifestations, % | 70 | 52 |
Leukopenia, % | 70 | 39 |
Lymphopenia, % | 60 | 28 |
Thrombocytopenia, % | 20 | 20 |
Immunology, % | 80 | 67 |
ANA, % | 100 | 100 |
Anti-DNA antibodies, % | 90 | 71 |
Anti-cardiolipin antibodies, % | 50 | 45 |
Anti-phospholipid antibody syndrome, % | 20 | 29 |
Vascular disease, % | 10 | 45 |
Median time since event, y (range) | 24 | 8 (2-36) |
Venous thrombosis, % | 10 | 29 |
Median time since event, y (range) | 24 | 16 (3-36) |
Arterial thrombosis, % | 0 | 19 |
Median time since event, y (range) | 8 (1-18) | |
Myocardial infarction, % | 0 | 15 |
Median time since event, y (range) | 7 (2-30) |
SLE indicates systemic lupus erythematosus; and ACR, American College of Rheumatology.