Immunophenotypic correlations between PTK7 and other hematopoietic stem cell markers
. | PTK7+ (n = 184), % . | PTK7− (n = 73), % . | P (χ2 test) . |
---|---|---|---|
HLA-DR+ | 73 | 84 | NS |
CD34+ | 66 | 33 | < .001 |
CD117+ | 91 | 26 | < .001 |
CD33+ | 89 | 89 | NS |
CD13+ | 79 | 64 | NS |
CD15+ | 35 | 76 | < .001 |
CD11b+ | 21 | 73 | < .001 |
. | PTK7+ (n = 184), % . | PTK7− (n = 73), % . | P (χ2 test) . |
---|---|---|---|
HLA-DR+ | 73 | 84 | NS |
CD34+ | 66 | 33 | < .001 |
CD117+ | 91 | 26 | < .001 |
CD33+ | 89 | 89 | NS |
CD13+ | 79 | 64 | NS |
CD15+ | 35 | 76 | < .001 |
CD11b+ | 21 | 73 | < .001 |
Expression of PTK7 was evaluated by 5-color flow cytometry in 257 AMLs. Gating was systematically performed on blast population using CD45dim, SSClow gate. Positivity was defined by an MFI ratio of 5-fold in at least 20% of the gated cells.
NS indicates not significant.