Table 2

Immunophenotypic correlations between PTK7 and other hematopoietic stem cell markers

PTK7+ (n = 184), %PTK7 (n = 73), %P2 test)
HLA-DR+ 73 84 NS 
CD34+ 66 33 < .001 
CD117+ 91 26 < .001 
CD33+ 89 89 NS 
CD13+ 79 64 NS 
CD15+ 35 76 < .001 
CD11b+ 21 73 < .001 
PTK7+ (n = 184), %PTK7 (n = 73), %P2 test)
HLA-DR+ 73 84 NS 
CD34+ 66 33 < .001 
CD117+ 91 26 < .001 
CD33+ 89 89 NS 
CD13+ 79 64 NS 
CD15+ 35 76 < .001 
CD11b+ 21 73 < .001 

Expression of PTK7 was evaluated by 5-color flow cytometry in 257 AMLs. Gating was systematically performed on blast population using CD45dim, SSClow gate. Positivity was defined by an MFI ratio of 5-fold in at least 20% of the gated cells.

NS indicates not significant.